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Chemicals & Small Molecules

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    Results for Chemicals & Small Molecules ( 97553 )

      • CDK12-IN-3

        Ref: T14990
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: DKK1,125.00

        CDK12-IN-3 (Legacy Tebubio ref. 282T14990). CDK12-IN-3 is a selective and potent CDK12 inhibitor with anti-tumor activity, which can be used to study malignant tumors.

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      • CMS-121

        Ref: T14991
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: DKK315.00

        CMS-121 (Legacy Tebubio ref. 282T14991). CMS-121, a quinolone derivative, is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage (EC50: 7 nM and 200 nM). CMS-121 shows strong neuroprotective, antioxidative, anti-inflammatory, and renoprotective activities.

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      • Raxatrigine hydrochloride

        Ref: T14992
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: DKK750.00

        Raxatrigine hydrochloride (Legacy Tebubio ref. 282T14992). Raxatrigine hydrochloride is a state-dependent sodium channel blocker and a Nav1.7 sodium channel inhibitor.

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      • Rociletinib hydrobromide

        Ref: T14993
        Sizes: 5 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: DKK338.00

        Rociletinib hydrobromide (Legacy Tebubio ref. 282T14993). Rociletinib hydrobromide is an orally delivered inhibitor of the mutant form of EGFR kinase (Kis: 21.5 nM and 303.3 nM for EGFR L858R/T790M and EGFR WT).

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      • Coelenterazine h

        Ref: T14994
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 500 μg
        From: DKK1,560.00

        Coelenterazine h (Legacy Tebubio ref. 282T14994). Coelenterazine H is a synthetic derivative of coelenterazine (a light-emitting biomolecule).Coelenterazine h (CLZN-h) is more sensitive to Ca 2+ than is the native complex, thus providing a valuable tool for measuring small changes in Ca 2+ concentrations.

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      • Concanamycin A

        Ref: T14995
        Sizes: 100 μg
        From: DKK2,325.00

        Concanamycin A (Legacy Tebubio ref. 282T14995). Concanamycin A (Folimycin), a polycyclic lactone antibiotic, is a selective inhibitor of vacuolar H+-ATPase (V-ATPase) and lysosomal acidification, and can be used to study inflammation.Concanamycin A enhances the immune clearance of infected progenitor cells by cytotoxic T lymphocytes, and inhibits Nef et al. from different branches of HIV and simian immunodeficiency virus. Concanamycin A enhances immune clearance of cytotoxic T lymphocytes from infected progenitor cells, inhibits the Nef allele from different branches of HIV and simian immunodeficiency virus, and can be used to study HIV infection.

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      • Congo Red

        Ref: T14996
        Sizes: 1 g, 500 mg, 1 mL * 10 mM (in DMSO)
        From: DKK263.00

        Congo Red (Legacy Tebubio ref. 282T14996). Congo Red (Direct Red 28) is an azo dye. It binding been used as a diagnostic test for the presence of amyloid in tissue sections.

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      • Conteltinib

        Ref: T14997
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: DKK855.00

        Conteltinib (Legacy Tebubio ref. 282T14997). Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK, and Pyk2.Conteltinib exhibits significant inhibition of FAK, overcomes hypoxia-mediated sorafenib resistance in hepatocellular carcinoma through inhibition of YAP signaling, and can be used in advanced ALK-positive non-small-cell lung cancer and lymphoma.

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      • Copanlisib dihydrochloride

        Ref: T14998
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg
        From: DKK405.00

        Copanlisib dihydrochloride (Legacy Tebubio ref. 282T14998). Copanlisib dihydrochloride (BAY 80-6946 dihydrochloride) is an ATP-competitive pan-class I PI3K inhibitor, with IC50 values of 0.5 nM for PI3Kα, 0.7 nM for PI3Kδ, 3.7 nM for PI3Kβ, and 6.4 nM for PI3Kγ. It exhibits superior antitumor activity and demonstrates more than 2,000-fold selectivity against other lipid and protein kinases, except for mTOR.

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