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Chemicals & Small Molecules

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    Results for Chemicals & Small Molecules ( 97556 )

      • Gboxin

        Ref: T15373
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: DKK473.00

        Gboxin (Legacy Tebubio ref. 282T15373). Gboxin is an inhibitor of oxidative phosphorylation that targets glioblastoma,inhibits the activity of F0F1 ATP synthase, with antitumour activity.

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      • Inavolisib

        Ref: T15375
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: DKK683.00

        Inavolisib (Legacy Tebubio ref. 282T15375). Inavolisib (GDC-0077) is an orally available selective PI3Kα inhibitor with an IC50 value of 0.038 nM.It exerts its activity by binding to the ATP-binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3.

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      • GDC-0339

        Ref: T15376
        Sizes: 25 mg, 100 mg, 50 mg
        From: DKK14,048.00

        GDC-0339 (Legacy Tebubio ref. 282T15376). GDC-0339 is discovered as a potential treatment of multiple myeloma. GDC-0339 is an orally bioavailable and well-tolerated inhibitor of the pan-Pim kinase (Kis: 0.03 nM, 0.1 nM, and 0.02 nM for Pim1, Pim2, and Pim3, respectively).

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      • Gemcitabine elaidate

        Ref: T15378
        Sizes: 5 mg, 2 mg
        From: DKK2,550.00

        Gemcitabine elaidate (Legacy Tebubio ref. 282T15378). Gemcitabine elaidate (CP-4126), is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracellularly by esterases, the prodrug gemcitabine is converted into the active metabolites difluorodeoxycytidine di- and tri-phosphate (dFdCDP and dFdCTP) by deoxycytidine kinase. dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis.

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      • Gemcitabine elaidate hydrochloride

        Ref: T15378L
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 10 mg
        From: DKK270.00

        Gemcitabine elaidate hydrochloride (Legacy Tebubio ref. 282T15378L). Gemcitabine elaidate (CP-4126) hydrochloride is a lipophilic pro-drug of Gemcitabine, converted to Gemcitabine by esterases for phosphorylation. Unlike gemcitabine, Gemcitabine elaidate hydrochloride can be administered orally, displaying schedule and dose-dependent toxicity and antitumor activity.

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      • GGsTop

        Ref: T15379
        Sizes: 1 mg
        From: DKK848.00

        GGsTop (Legacy Tebubio ref. 282T15379). GGsTop (Nahlsgen) is a highly selective and irreversible inhibitor of γ-glutamyltransferase (GGT) with antiaging activity.

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      • Gisadenafil

        Ref: T15381
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: DKK1,665.00

        Gisadenafil (Legacy Tebubio ref. 282T15381). Gisadenafil (UK-369003), a selective inhibitor of phosphodiesterase 5 (PDE5) with an IC50 of 3.6 nM, prevents the degradation of cGMP.

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      • GI 181771

        Ref: T15382
        Sizes: 1 mg, 5 mg, 50 mg
        From: DKK1,665.00

        GI 181771 (Legacy Tebubio ref. 282T15382). GI 181771 is an agonist of the cholecystokinin 1 receptor. GI 181771 can be used in studies about obesity.

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      • Glesatinib hydrochloride

        Ref: T15383
        Sizes: 25 mg, 100 mg, 50 mg
        From: DKK8,123.00

        Glesatinib hydrochloride (Legacy Tebubio ref. 282T15383). Glesatinib hydrochloride is an orally active and potent dual inhibitor of MET/SMO. Glesatinib hydrochloride is also a tyrosine kinase inhibitor. It antagonizes P-glycoprotein mediated multidrug resistance (MDR) in NSCLC.

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