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Chemicals & Small Molecules

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    Results for Chemicals & Small Molecules ( 97587 )

      • Myoseverin

        Ref: T21632
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: DKK263.00

        Myoseverin (Legacy Tebubio ref. 282T21632). Myoseverin, an inducer of the reversible fission of multinucleated myotubes into mononucleated fragments, affecting the expression of a variety of growth factor, immunomodulatory, extracellular matrix-remodeling, and stress response genes, consistent with the activation of pathways involved in wound healing and tissue regeneration.

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      • N-3-oxo-dodecanoyl-L-Homoserine lactone

        Ref: T21633
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 10 mg
        From: DKK623.00

        N-3-oxo-dodecanoyl-L-Homoserine lactone (Legacy Tebubio ref. 282T21633). N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL), a quorum-sensing signaling molecule synthesized by P. aeruginosa and specific B. cepacia complex strains [1][2], facilitates bacterial gene expression modulation in response to cell density escalation and triggers IL-8 production in 16HBE human bronchial epithelial cells [3].

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      • N-Oxalylglycine

        Ref: T21634
        Sizes: 100 mg, 50 mg, 500 mg, 200 mg
        From: DKK360.00

        N-Oxalylglycine (Legacy Tebubio ref. 282T21634). N-Oxalylglycine (Oxalylglycine) is a cell permeable inhibitor of α-ketoglutarate-dependent enzymes.

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      • PD184161

        Ref: T21635
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 200 mg, 2 mg
        From: DKK278.00

        PD184161 (Legacy Tebubio ref. 282T21635). PD184161 is a novel, orally-active MEK inhibitor. PD184161 inhibited MEK activity (IC50 = 10-100 nM) in a time- and concentration-dependent manner[1].

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      • SB-505124 hydrochloride

        Ref: T21637
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg
        From: DKK300.00

        SB-505124 hydrochloride (Legacy Tebubio ref. 282T21637). SB-505124 hydrochloride (SB505124 hydrochloride) is an orally available, selective and potent inhibitor of TGF-β type I receptors (ALK4, ALK5, ALK7) with IC50 values of 129 nM and 47 nM for ALK4 and ALK5, respectively. SB-505124 hydrochloride inhibits IL-6 production by synovial explants and reduces Th17 differentiation in mice by decreasing Il17a and Rorc gene expression and IL-17 protein production.SB-505124 hydrochloride is used in the study of colorectal cancer.

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      • Wiskostatin

        Ref: T2164
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: DKK330.00

        Wiskostatin (Legacy Tebubio ref. 282T2164). Wiskostatin is a selective inhibitor of N-WASP, a ubiquitously expressed member of the Wiskott-Aldrich Syndrome protein (WASp) family that regulates actin polymerization.

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      • Talinolol

        Ref: T21640
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: DKK585.00

        Talinolol (Legacy Tebubio ref. 282T21640). (±)-Talinolol is a selective β1 adrenoceptor antagonist well known for its cardioprotective and antihypertensive activity.

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      • Vandetanib hydrochloride

        Ref: T21641
        Sizes: 25 mg, 100 mg, 50 mg
        From: DKK12,945.00

        Vandetanib hydrochloride (Legacy Tebubio ref. 282T21641). Vandetanib hydrochloride (D6474 hydrochloride) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity with an IC50 of 40 nM. It also exhibits activity against VEGFR3/FLT4 tyrosine kinase activity (IC50 = 110 nM) and EGFR/HER1 (IC50 = 500 nM) [1].

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      • 4,5,6,7-Tetrabromobenzimidazole

        Ref: T21642
        Sizes: 25 mg
        From: DKK3,645.00

        4,5,6,7-Tetrabromobenzimidazole (Legacy Tebubio ref. 282T21642). 4,5,6,7-Tetrabromobenzimidazole is a selective, ATP-competitive inhibitor of protein kinase CK2 [1].

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