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Chemicals & Small Molecules

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    Results for Chemicals & Small Molecules ( 97587 )

      • LDN-211904 oxalate

        Ref: T21762
        Sizes: 1 mg, 5 mg
        From: DKK1,943.00

        LDN-211904 oxalate (Legacy Tebubio ref. 282T21762). LDN-211904 oxalate (compound 32), a potent and selective EphB3 inhibitor, demonstrates an IC50 of 0.079 μM and shows good metabolic stability in mouse liver microsomes. When combined with cetuximab, it may effectively inhibit STAT3-activated CSC stemness and cetuximab resistance in CRC [1] [2].

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      • Lenalidomide hydrochloride

        Ref: T21763
        Sizes: 25 mg, 100 mg, 50 mg
        From: DKK12,945.00

        Lenalidomide hydrochloride (Legacy Tebubio ref. 282T21763). Lenalidomide hydrochloride (CC-5013 hydrochloride), a Thalidomide derivative, functions as molecular glue and serves as an orally active immunomodulator. As a ligand for the ubiquitin E3 ligase cereblon (CRBN), it facilitates the selective ubiquitination and degradation of the lymphoid transcription factors IKZF1 and IKZF3 through the CRBN-CRL4 ubiquitin ligase. Specifically, Lenalidomide hydrochloride inhibits the growth of mature B-cell lymphomas, including multiple myeloma, and promotes IL-2 release from T cells [1] [2].

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      • MCC-555

        Ref: T21764
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: DKK548.00

        MCC-555 (Legacy Tebubio ref. 282T21764). MCC-555 (Isaglitazone) is a PPARα and PPARγ agonist exerting antihyperglycemic effects.

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      • ML352

        Ref: T21766
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: DKK293.00

        ML352 (Legacy Tebubio ref. 282T21766). ML352 is a selective and potent inhibitor of the presynaptic choline transporter (CHT), inhibits non-competitive choline uptake.

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      • MS37452

        Ref: T21767
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: DKK405.00

        MS37452 (Legacy Tebubio ref. 282T21767). MS37452 is a competitive inhibitor of CBX7 chromodomain binding to H3K27me3 (Ki = 43 µM).

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      • PF-562271 hydrochloride

        Ref: T21768
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg
        From: DKK608.00

        PF-562271 hydrochloride (Legacy Tebubio ref. 282T21768). PF-562271 hydrochloride (PF-562271 HCl) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.

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      • β-Pompilidotoxin Acetate

        Ref: T21769L
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: DKK330.00

        β-Pompilidotoxin Acetate (Legacy Tebubio ref. 282T21769L). β-Pompilidotoxin Acetate is a wasp venom peptide. β-Pompilidotoxin Acetate can slow sodium channel inactivation and increase steady-state sodium current in cells.

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      • Kaempferol

        Ref: T2177
        Sizes: 100 mg, 50 mg, 500 mg, 200 mg, 1 mL * 10 mM (in DMSO)
        From: DKK398.00

        Kaempferol (Legacy Tebubio ref. 282T2177). Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ. Kaempferol has a wide range of antitumor, anti-inflammatory, antioxidant, antibacterial and antiviral activities.

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      • Pyoluteorin

        Ref: T21771
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: DKK1,680.00

        Pyoluteorin (Legacy Tebubio ref. 282T21771). Pyoluteorin is an antibiotic that inhibits Oomycete fungi, including the plant pathogen Pythium ultimum, and suppresses related plant diseases. Additionally, Pyoluteorin induces apoptosis in human triple-negative breast cancer (MDA-MB-231) cells in vitro.

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