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Chemicals & Small Molecules

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    Results for Chemicals & Small Molecules ( 97581 )

      • GSK3β inhibitor II

        Ref: T21956
        Sizes: 25 mg, 100 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: DKK263.00

        GSK3β inhibitor II (Legacy Tebubio ref. 282T21956). GSK3β inhibitor II is a GSK3β inhibitor. GSK3β inhibitor II exhibits the research potential of Alzheimer's disease (AD).

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      • Guanabenz hydrochloride

        Ref: T21957
        Sizes: 100 mg, 50 mg, 500 mg, 200 mg, 1 mL * 10 mM (in DMSO)
        From: DKK248.00

        Guanabenz hydrochloride (Legacy Tebubio ref. 282T21957). Guanabenz hydrochloride (NE56490) is an orally active α2-adrenoceptor agonist with hypotensive effects.

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      • Fipronil

        Ref: T2196
        Sizes: 1 g, 100 mg, 50 mg, 500 mg, 200 mg, 1 mL * 10 mM (in DMSO)
        From: DKK248.00

        Fipronil (Legacy Tebubio ref. 282T2196). Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family. Fipronil is a broad-spectrum insecticide that disrupts the insect central nervous system by blocking GABA-gated chloride channels and glutamate-gated chloride (GluCl) channels, resulting in central nervous system toxicity. This causes hyperexcitation of contaminated insects' nerves and muscles. Specificity of fipronil on insects may come from a better efficacy on GABA receptor, but also because GluCl channels do not exist in mammals.

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      • HZ52

        Ref: T21962
        Sizes: 1 mg, 5 mg, 25 mg, 10 mg
        From: DKK795.00

        HZ52 (Legacy Tebubio ref. 282T21962). HZ52 is a potent, reversible 5-lipoxygenase (5-LO) inhibitor that blocks leukotriene (LTs) synthesis with an IC50 of 0.7 μM in intact human polymorphonuclear leukocytes [1].

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      • MBCQ

        Ref: T21965
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 1 mL * 10 mM (in DMSO)
        From: DKK338.00

        MBCQ (Legacy Tebubio ref. 282T21965). MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5.

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      • MeBIO

        Ref: T21966
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: DKK285.00

        MeBIO (Legacy Tebubio ref. 282T21966). MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β.

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      • MEG hemisulfate

        Ref: T21967
        Sizes: 1 mg, 5 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: DKK263.00

        MEG hemisulfate (Legacy Tebubio ref. 282T21967). MEG hemisulfate (Mercaptoethylguanidine hemisulfate) acts as a highly potent and selective suppressor of inducible NO synthase (iNOS), demonstrating EC50 values of 11.5 μM for iNOS, 110 μM for ecNOS, and 60 μM for bNOS in tissue homogenates. It is notably effective as a peroxynitrite scavenger and blocks peroxynitrite-triggered oxidative mechanisms. Furthermore, this compound offers protective benefits across various experimental inflammation prototypes, such as ischemia/reperfusion injury, hemorrhagic shock, periodontitis, inflammatory bowel disease, and both endotoxic and septic shock.

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      • MG-262

        Ref: T21968
        Sizes: 1 mg, 200 μg
        From: DKK6,368.00

        MG-262 (Legacy Tebubio ref. 282T21968). MG-262 is a reversible proteasome inhibitor with multiple biological activities (MGCD-162, Mills 2004) (Morrison et al., 2005, Li et al., 2006) (Tang et al., 2006, Zhang et al., 2007).

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      • ML-095 hydrochloride

        Ref: T21969
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: DKK278.00

        ML-095 hydrochloride (Legacy Tebubio ref. 282T21969). ML-095 hydrochloride (CID-25067483 hydrochloride) is a specific placental alkaline phosphatase inhibitor. It inhibits PLAP, TNAP and IAP with IC50 of 2.1, >100 and 53 μM, respectively.

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