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Chemicals & Small Molecules

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    Results for Chemicals & Small Molecules ( 97581 )

      • PKI 14-22 amide, myristoylated Acetate

        Ref: T21983L
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: DKK2,543.00

        PKI 14-22 amide, myristoylated Acetate (Legacy Tebubio ref. 282T21983L). PKI 14-22 amide, myristoylated Acetate inhibit cAMP-dependent protein kinase (PKA) and blocks hyperalgesia produced by spinal administration of 8-bromo-cAMP. 

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      • PT-1

        Ref: T21984
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 10 mg
        From: DKK300.00

        PT-1 (Legacy Tebubio ref. 282T21984). PT-1 is an AMPKα1 activator that dose-dependently activates AMPK α1394, α1335, and α2398 and enhances AMPK phosphorylation.

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      • SSR 69071

        Ref: T21989
        Sizes: 1 mg, 5 mg, 10 mg
        From: DKK668.00

        SSR 69071 (Legacy Tebubio ref. 282T21989). SSR69071 is a potent, orally active, and selective inhibitor of neutrophil elastase, displaying higher affinity for human elastase (Ki = 0.0168 nM) compared to rat (Ki = 3 nM), mouse (Ki = 1.8 nM), and rabbit (Ki = 58 nM) elastases [2]. It reduces myocardial infarct size following ischemia-reperfusion injury [1] and has potential for treating chronic obstructive pulmonary diseases, asthma, emphysema, cystic fibrosis, and various inflammatory diseases.

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      • Myclobutanil

        Ref: T2199
        Sizes: 100 mg, 50 mg, 500 mg, 1 mL * 10 mM (in DMSO)
        From: DKK338.00

        Myclobutanil (Legacy Tebubio ref. 282T2199). Myclobutanil (Systhane) is a triazole chemical used as a fungicide. It is a steroid demethylation inhibitor, specifically inhibiting ergosterol biosynthesis. Ergosterol is a critical component of fungal cell membranes.

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      • Vacuolin-1

        Ref: T21992
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg
        From: DKK270.00

        Vacuolin-1 (Legacy Tebubio ref. 282T21992). Vacuolin-1 is a cell-permeable inhibitor of Ca2+ dependent fusion of lysosomes to the cell membrane. It acts by inhibiting release of lysosomal content.vacuolin‐1 is a potent and selective PIKfyve inhibitor and inhibits late‐stage autophagy by impairing lysosomal maturation

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      • XAP044

        Ref: T21995
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: DKK480.00

        XAP044 (Legacy Tebubio ref. 282T21995). XAP044 is a mGlu7-selective antagonist which inhibits lateral amygdala long term potentiation (LTP) in brain slices from wild type mice with a half-maximal blockade at 88 nm[1].

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      • Zoniporide hydrochloride

        Ref: T21996
        Sizes: 1 mg, 5 mg, 25 mg, 10 mg
        From: DKK488.00

        Zoniporide hydrochloride (Legacy Tebubio ref. 282T21996). Zoniporide hydrochloride is a selective inhibitor of NHE-1 with IC50 of 14 nM which is >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride shows an IC50 of 59 nM for NHE-1-dependent swelling of human platelets.

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      • Zoniporide

        Ref: T21996L
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg
        From: DKK1,665.00

        Zoniporide (Legacy Tebubio ref. 282T21996L). Zoniporide (CP-597396) is an NHE-1 inhibitor that inhibits the uptake of 22Na+ by fibroblasts expressing human NHE-1 in a concentration-dependent manner, inhibits platelet swelling, and can be used in the study of cardiovascular diseases.

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      • (±)-J 113397

        Ref: T21999
        Sizes: 25 mg, 100 mg, 50 mg
        From: DKK7,928.00

        (±)-J 113397 (Legacy Tebubio ref. 282T21999). (±)-J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist (K(i): cloned human ORL1=1.8 nM). J-113397 inhibited nociceptin/orphanin FQ-stimulated GTPγS binding to CHO cells expressing ORL1 with an IC50 value of 5.3 nM. J-113397 can be used for researching the physiological roles of nociceptin/orphanin FQ [1].

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