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Chemicals & Small Molecules

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    Results for Chemicals & Small Molecules ( 97581 )

      • Adrenosterone

        Ref: T2207
        Sizes: 50 mg, 1 mL * 10 mM (in DMSO)
        From: DKK338.00

        Adrenosterone (Legacy Tebubio ref. 282T2207). Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex.

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      • DBIBB

        Ref: T22070
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: DKK300.00

        DBIBB (Legacy Tebubio ref. 282T22070). DBIBB is a non-lipid agonist of specific lysophosphatidic acid (LPA2) type 2 G-protein-coupled receptor. It is a potentially active molecule for the treatment of acute radiation syndrome caused by high intensity gamma rays on hematopoietic and gastrointestinal systems. It is an intermediate in organic synthesis and drug research. DBIBB can be used to prepare various compounds that reduce gastrointestinal radiation syndrome, increase intestinal crypt survival and intestinal cell proliferation, and reduce cell apoptosis.

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      • Eggmanone

        Ref: T22077
        Sizes: 1 mg, 5 mg, 10 mg
        From: DKK1,688.00

        Eggmanone (Legacy Tebubio ref. 282T22077). Eggmanone (EGM1) is a potent, selective phosphodiesterase 4 (PDE4) antagonist, exhibiting an IC50 of 72 nM specifically for PDE4D3. It shows 40- to 50-fold greater selectivity for PDE4D3 over other phosphodiesterases. The mechanism of action involves PDE4 selective antagonism by Eggmanone, which activates protein kinase A, culminating in the blockade of the Hedgehog (Hh) signaling pathway [1].

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      • Bacitracin Zinc

        Ref: T2208
        Sizes: 1 g, 500 mg, 200 mg
        From: DKK308.00

        Bacitracin Zinc (Legacy Tebubio ref. 282T2208). Bacitracin Zinc is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, interference for inhibition of cleavage of Tyr from Met-enkephalin(IC50=10 μM).

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      • FBPase-1 inhibitor-1

        Ref: T22081
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)
        From: DKK450.00

        FBPase-1 inhibitor-1 (Legacy Tebubio ref. 282T22081). FBPase-1 inhibitor-1 (Fructose 1,6-bisphosphatase-1 Inhibitor) is a fructose 1,6-bisphosphatase-1 inhibitor.

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      • HA 155

        Ref: T22086
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg
        From: DKK270.00

        HA 155 (Legacy Tebubio ref. 282T22086). HA 155 (Autotaxin Inhibitor IV) is a boronic acid-based compound, inhibiting ATX with IC50 of 5.7 nM by selectively binding to its catalytic threonine.

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      • HLI 373

        Ref: T22087
        Sizes: 25 mg, 50 mg
        From: DKK13,853.00

        HLI 373 (Legacy Tebubio ref. 282T22087). HLI373 is an efficacious Hdm2 inhibitor, an ubiquitin ligase (E3), effective in inducing apoptosis of several tumor cells sensitive to DNA-damaging agents [1], and also shows prominent antimalarial activity [2].

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      • HPI 1

        Ref: T22089
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)
        From: DKK338.00

        HPI 1 (Legacy Tebubio ref. 282T22089). HPI 1 is a hedgehog (Hh) signaling inhibitor. Inhibits Sonic hedgehog (Shh)-, SAG- and Gli-induced Hh pathway activation in Shh-LIGHT2 cells (IC50 values are 1.5, 1.5, 4, and 6 μM for Shh-, SAG-, Gli2- and Gli1-induced activation).

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      • Serotonin hydrochloride

        Ref: T2209
        Sizes: 25 mg, 100 mg, 50 mg, 200 mg, 1 mL * 10 mM (in DMSO)
        From: DKK263.00

        Serotonin hydrochloride (Legacy Tebubio ref. 282T2209). Serotonin hydrochloride (Serotonin HCl) is an endogenous 5-HT receptor agonist, a monoamine neurotransmitter in the CNS, and a catechol O-methyltransferase (COMT) inhibitor(Ki=44 μM).

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