Viral Vectors & Particles

Human Kappa Opioid receptor packaged in BacMam for expression in mammalian cells. BacMam provides even, near 100% transduction efficiency in HEK293 cells as well as expression in many other cell lines, iPSCs, and primary cultures. Expression is easily titrateable to your experimental needs or to adjust assay sensitivity. Co-express with Montana Molecular sensors including the cADDis and Borealis sensors for cAMP and arrestin signaling. This kit includes KOR receptor BacMam and 500mM sodium butyrate in H2O.

Mu Opioid receptor packaged in BacMam for expression in mammalian cells. BacMam provides even, near 100% transduction efficiency in HEK293 cells as well as expression in many other cell lines, iPSCs, and primary cultures. Expression is easily titrateable to your experimental needs or to adjust assay sensitivity. Co-express with Montana Molecular sensors including the cADDis and Borealis sensors for cAMP and arrestin signaling. This kit includes MOR receptor BacMam and 500mM sodium butyrate in H2O.

Mu Opioid receptor packaged in BacMam for expression in mammalian cells. BacMam provides even, near 100% transduction efficiency in HEK293 cells as well as expression in many other cell lines, iPSCs, and primary cultures. Expression is easily titrateable to your experimental needs or to adjust assay sensitivity. Co-express with Montana Molecular sensors including the cADDis and Borealis sensors for cAMP and arrestin signaling. This kit includes MOR receptor BacMam and 500mM sodium butyrate in H2O.

Cannabinoid CB1 receptor packaged in BacMam for expression in mammalian cells. BacMam provides even, near 100% transduction efficiency in HEK293 cells as well as expression in many other cell lines, iPSCs, and primary cultures. Expression is easily titrateable to your experimental needs or to adjust assay sensitivity. Co-express with Montana Molecular sensors including the cADDis sensor for cyclic AMP (cAMP) signaling. This kit includes CB1 receptor BacMam and 500mM sodium butyrate in H2O.

Human Angiotensin II Type I receptor packaged in BacMam for expression in mammalian cells. BacMam provides even, near 100% transduction efficiency in HEK293 cells as well as expression in many other cell lines, iPSCs, and primary cultures. Expression is easily titrateable to your experimental needs or to adjust assay sensitivity. Co-express with Montana Molecular sensors including Borealis arrestin, DAG, PIP2, and Calcium signaling assays. This kit includes AT1R receptor BacMam and 500mM sodium butyrate in H2O.

Human Angiotensin II Type I receptor packaged in BacMam for expression in mammalian cells. BacMam provides even, near 100% transduction efficiency in HEK293 cells as well as expression in many other cell lines, iPSCs, and primary cultures. Expression is easily titrateable to your experimental needs or to adjust assay sensitivity. Co-express with Montana Molecular sensors including Borealis arrestin, DAG, PIP2, and Calcium signaling assays. This kit includes AT1R receptor BacMam and 500mM sodium butyrate in H2O.

The anti-CD19 CAR lentiviruses are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to infect almost all types of mammalian cells, including primary and non-dividing cells. These viruses transduce the ScFv portion of anti-CD19 (clone FMC63) linked to 2^nd generation CAR (Chimeric Antigen Receptor) containing CD8 hinge and transmembrane domains, 4-1BB and CD3ζ signaling domains . Note: This product transduces the same construct as the anti-CD19 CAR Lentivirus (CD19 ScFv-CD8-4-1BB-CD3ζ) (BPS Bioscience #78600), but differs in key aspects: 78601 is constructed with a SIN lentivector while 78600 is not. 78601 does not contain an antibiotic for selection while 78600 contains a puromycin selection so the transduced cells can be selected with puromycin.

The anti-CD19/CD22 Bispecific CAR lentiviruses are replication incompetent, HIV-based, VSV-G-pseudotyped lentiviral particles that are ready to infect almost all types of mammalian cells, including primary and non-dividing cells. These viruses transduce the ScFv (single-chain variable fragments) of anti-CD19 (clone FMC63) and anti-CD22 (clone m971) linked to a 2^nd generation CAR (Chimeric Antigen Receptor) containing CD8 hinge and transmembrane domains, and the 4-1BB and CD3ζ signaling domains.

Severe acute respiratory syndrome (SARS) was the first new infectious disease identified in the twenty-first century. It is a viral respiratory disease caused by severe acute respiratory syndrome coronavirus (SARS-CoV-1). The first known cases occurred in November 2002, and the syndrome caused the 2002-2004 SARS outbreak. Since 2004, no cases of SARS-CoV-1 have been reported worldwide. A virus very similar to SARS-CoV-1 was discovered in late 2019. This virus, named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is the causative pathogen of COVID-19, the spread of which started the COVID-19 pandemic. SARS-CoV-1 attaches to the host cell surface before entering the cell. The Spike protein on the virus recognizes and binds to the Angiotensin-Converting Enzyme 2 (ACE2) receptor found on the surface of human airway epithelia as well as lung parenchyma. Drugs targeting the interaction between the Spike protein of SARS-CoV-1 and ACE2 may offer protection against the viral infe