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    Results for Cell Lysate ( 16283 )

      • Ref: W09-K01-MT9
        Sizes: 100 µg

        ROBO-1 (also called Roundabout homolog 1 precursor and Deleted in U twenty twenty (DUTT)) functions as a receptor for SLIT1 and SLIT2.  The SLIT proteins are thought to act as a molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex.  ROBO-1 may also be required for lung development. ROBO-1 is a type I membrane protein.  ROBO-1 is a widely expressed protein with the exception of the kidney.  Defects in ROBO1 may be a cause of breast and lung cancer. ROBO-1 maps within a region of overlapping homozygous deletions characterized in both small cell lung cancer cell lines (SCLC) and in a breast cancer cell line.

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      • Ref: W09-K01-MU1
        Sizes: 100 µg

        ERK2 antibodies detect the ERK2 isoform. Mitogen activated protein kinase 1, also known as MAPK1, ERK, or ERK2, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. ERK1 and ERK2 are activated by MEK1 and MEK2 in the B-raf signaling pathway resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Human ERK1 and ERK2 are 84% identical in sequence and share common functionality in cells.

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      • Ref: PL-NH-100
        Sizes: 100mL

        platelet lysate, research, 100mL

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      • Ref: PL-NH-500
        Sizes: 500mL

        platelet lysate, research, 500mL

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      • Ref: PL-PR-100
        Sizes: 100mL

        pathogen reduced platelet lysate, 100mL

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      • Ref: PL-PR-500
        Sizes: 500mL

        pathogen reduced platelet lysate, 500mL

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      • Ref: PL-SP-100
        Sizes: 100mL

        platelet lysate, clinical, 100mL

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      • Ref: PL-SP-500
        Sizes: 500mL

        platelet lysate, clinical, 500mL

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      • Ref: TL-PR-150C
        Sizes: 100mL

        pathogen reduced platelet lysate, 100mL bag

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