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Chemicals & Small Molecules

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    Results for Chemicals & Small Molecules ( 97553 )

      • Acitretin sodium

        Ref: T22548
        Sizes: 25 mg, 100 mg, 50 mg

        Acitretin sodium (Legacy Tebubio ref. 282T22548). Acitretin sodium is a second-generation, systemic retinoid. It is also has been used in the treatment of psoriasis.

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      • ACPT-I

        Ref: T22549
        Sizes: 1 mg, 5 mg, 10 mg

        ACPT-I (Legacy Tebubio ref. 282T22549). Agonist for group III mGlu receptors

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      • SB-743921 hydrochloride

        Ref: T2255
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 1 mL * 10 mM (in DMSO)

        SB-743921 hydrochloride (Legacy Tebubio ref. 282T2255). SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).

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      • ACPT-II

        Ref: T22550
        Sizes: 50 mg, 10 mg

        ACPT-II (Legacy Tebubio ref. 282T22550). metabotropic receptor antagonist

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      • AD57 (hydrochloride)

        Ref: T22552
        Sizes: 1 mg, 5 mg, 10 mg

        AD57 (hydrochloride) (Legacy Tebubio ref. 282T22552). AD57, as polypharmacological cancer therapeutic, is designed to regulate multiple targets related to cancer blocks the receptor tyrosine kinase RET in Drosophila (IC50: 2 nM). AD57 effectively suppresses tyrosine kinase RET, weakens the activity of numerous other kinases, and interferes with kinases downstream of RET, including Raf, Src, and S6K, providing further efficacy in preventing signaling leading to invasion, proliferation, and metabolism-related to cancer. Tyrosine kinase RET is probably sufficient to initiate a series of transformation events including medullary thyroid carcinoma, multiple endocrine neoplasias type 2A, and 2B.

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      • AD57

        Ref: T22552L
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 2 mg, 1 mL * 10 mM (in DMSO)

        AD57 (Legacy Tebubio ref. 282T22552L). AD57 is a potent inhibitor of both c-Src and Abl with IC50 of 0.025 μM and 0.041 μM, respectively.

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      • Adaphostin

        Ref: T22553
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg

        Adaphostin (Legacy Tebubio ref. 282T22553). Adaphostin (NSC-680410) is a p210Bcr/Abl tyrosine kinase inhibitor with IC50 of 14 μM.

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      • Adenosine Kinase Inhibitor (hydrate)

        Ref: T22554
        Sizes: 1 mg, 5 mg, 10 mg

        Adenosine Kinase Inhibitor (hydrate) (Legacy Tebubio ref. 282T22554). Adenosine kinase is the key metabolizing enzyme regulating cellular adenosine concentrations. Inhibition of adenosine kinase can selectively enhance the protective actions of adenosine during tissue trauma without producing the nonspecific effects associated with the systemic administration of adenosine receptor agonists (IC50: 1.7 nM in cell-free assays).

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      • AF-DX 384 free base

        Ref: T22555
        Sizes: 1 mg, 5 mg, 25 mg, 10 mg

        AF-DX 384 free base (Legacy Tebubio ref. 282T22555). AF-DX 384 free base is a selective and efficient M2 muscarinic acetylcholine receptor (M2 mAChR) and M4 muscarinic acetylcholine receptor (M4 mAChR) antagonist. It can be used for research on neurodegenerative diseases like Parkinson’s.

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