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Chemicals & Small Molecules

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    Results for Chemicals & Small Molecules ( 97788 )

      • Lirentelimab

        Ref: T76869
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 10 mg

        Lirentelimab (AK002) is a humanized anti-sialic acid-binding immunoglobulin-like lectin-8 (Siglec-8) antibody that induces apoptosis of IL-5-activated eosinophils and inhibits IL-5-mediated mast cell activation, and is used in the study of refractory inert systemic mastocytosis and allergic conjunctivitis.

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      • Volagidemab

        Ref: T76876
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 10 mg

        Volagidemab (AMG-477) is a glucagon receptor (GCGR) antagonist and monoclonal antibody for the study of endocrine and metabolic diseases such as type 1 diabetes (T1D) and hypoglycemia.

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      • Vesencumab

        Ref: T76879
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 10 mg

        Vesencumab (MNRP-1685A) is an IG1 antibody targeting NRP-1 with anti-angiogenic and anti-tumor activity that reduces the number of globules formed by the SUM159 and Hs578T cell lines. Vesencumab inhibits EGFR and PDGFRα activation and can be used to study solid tumors.

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      • Rinucumab

        Ref: T76887
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg

        Rinucumab (REGN 2176) is an anti-platelet-derived growth factor (PDGF) IgG4-like monoclonal antibody that acts by binding to the PDGF-β receptor and can be used to study age-related macular degeneration.

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      • Avizakimab

        Ref: T76914
        Sizes: 1 mg, 5 mg

        Avizakimab (BOS161721), a humanized IgG1 monoclonal antibody, specifically targets interleukin-21 [1].

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      • Axatilimab

        Ref: T76915
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 10 mg

        Axatilimab (SNDX-6352) is a human IgG4 antibody targeting the colony-stimulating factor 1 receptor (CSF-1R), which can be used for the study of immune system disorders and respiratory diseases.

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      • Barecetamab

        Ref: T76918
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg

        Barecetamab (ISU-104) is a humanized monoclonal antibody against tyrosine protein kinase ErbB3 with anticancer activity for use in investigational stage malignant solid tumors.

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      • Bepranemab

        Ref: T76926
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 10 mg

        Bepranemab (UCB 0107) is a humanized anti-tau monoclonal antibody of the IgG class for the study of Alzheimer's disease (AD) and tau protein disorders.

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      • Zelminemab

        Ref: T76949
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 10 mg

        Zelminemab (AMG-301) is a humanized monoclonal antibody targeting the pituitary adenylate cyclase-activating polypeptide type I receptor (ADCYAP1R1) for use in neurological disorders.

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