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Chemicals & Small Molecules

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    Results for Chemicals & Small Molecules ( 97788 )

      • Mezagitamab

        Ref: T77084
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 10 mg

        Mezagitamab (TAK-079) is a fully humanized IgG1λ monoclonal antibody against CD38 with high affinity for CD38-expressing cells (including plasma mother cells, plasma cells, and natural killer cells), which depletes CD38-expressing tumor cells through antibody- and complement-dependent cytotoxicity Mezagitamab may be used in the study of recurrent/refractory multiple myeloma (RRMM), which is the most common form of cancer. multiple myeloma (RRMM) and primary thrombocytopenic purpura (ITP).

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      • Nofazinlimab

        Ref: T77102
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg

        Nofazinlimab (CS1003) is a human anti-PD-1 IgG4 monoclonal antibody used to study unresectable hepatocellular carcinoma (uHCC) and metastatic colorectal cancer.

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      • Nurulimab

        Ref: T77103
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 10 mg

        Nurulimab (BCD-145) is an anti-cytotoxic T-lymphocyte antigen 4 (CTLA-4) human monoclonal antibody with anti-cancer activity for the study of skin and musculoskeletal diseases.

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      • Plonmarlimab

        Ref: T77116
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg

        Plonmarlimab (TJ003234) is an anti-macrophage colony-stimulating factor (GM-CSF) monoclonal antibody with potential antiviral activity for the study of immune diseases and novel coronavirus infections.

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      • Etrolizumab

        Ref: T77154
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 10 mg

        Etrolizumab (rhuMAb Beta7) is a humanized intestinal-selective anti-β7 integrin monoclonal antibody that selectively blocks the transport and retention of lymphocytes in the intestinal tract for the study of inflammatory bowel disease (IBD).

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      • Methylene Violet 3RAX

        Ref: T77235
        Sizes: 25 mg, 100 mg, 50 mg, 500 mg, 10 mg

        Methylene Violet 3RAX is a cationic dye, a potential photosensitizer in photodynamic therapy, with antitumor activity that alters the molecular structure of DNA, disrupts the modules of DNA, and induces the production of reactive monoclinic oxygen species, which are used to stain the mitochondria of cells.Methylene Violet 3RAX inhibits the subcellular localization of cancer cells by severing the Methylene Violet 3RAX inhibits subcellular localization of cancer cells, leading to cell death by cutting DNA strands in tumor cells.

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      • Lifastuzumab

        Ref: T77384
        Sizes: 1 mg, 5 mg, 25 mg, 10 mg

        lifastuzumAb is a humanized IgG1-like monoclonal antibody against NaPi2b, often coupled with the anti-mitotic agent monomethyl auristatin E, which inhibits cell division by blocking the polymerization of microtubule proteins.

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      • Refanezumab

        Ref: T77388
        Sizes: 1 mg, 5 mg, 25 mg, 10 mg

        Refanezumab (GSK249320) is an IgG1 humanized monoclonal antibody that crosses the blood-brain barrier (BBB) and targets myelin-associated glycoprotein (MAG) for the study of neurological and cardiovascular diseases.

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      • Vadastuximab

        Ref: T77389
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 10 mg

        Vadastuximab (Anti-Human CD33 Recombinant Antibody) is a humanized anti-CD33 monoclonal antibody that can be used for the synthesis of the ADC compound Vadastuximab talirine and for the study of acute myeloid leukemia (AML).

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