Chemicals & Small Molecules

Avizakimab (BOS161721), a humanized IgG1 monoclonal antibody, specifically targets interleukin-21 [1].

Axatilimab (SNDX-6352) is a human IgG4 antibody targeting the colony-stimulating factor 1 receptor (CSF-1R), which can be used for the study of immune system disorders and respiratory diseases.

Barecetamab (ISU-104) is a humanized monoclonal antibody against tyrosine protein kinase ErbB3 with anticancer activity for use in investigational stage malignant solid tumors.

Bepranemab (UCB 0107) is a humanized anti-tau monoclonal antibody of the IgG class for the study of Alzheimer's disease (AD) and tau protein disorders.

Zelminemab (AMG-301) is a humanized monoclonal antibody targeting the pituitary adenylate cyclase-activating polypeptide type I receptor (ADCYAP1R1) for use in neurological disorders.

Vilobelimab (CaCP-29) is a human-mouse chimeric IgG antibody targeting human complement component 5a, a C5a inhibitor that inhibits neutrophil activation, and can be used for the study of systemic inflammation caused by SARS-CoV-2 infection.

Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic activity that blocks the platelet αIIbβ3 integrin interac- with brinogen and bronectin, and can be used in the study of cardiovascular disease.

Teropavimab (3BNC117-LS), an antibody, is utilized in the research of HIV infection [1].

Ezabenlimab (BI-754091) is a humanized monoclonal antibody targeting programmed cell death protein-1 with antitumor activity that blocks the interaction of PD-1 with PD-L1 and PD-L2, inhibits tumor growth in vivo, and can be used to study advanced solid tumors.