Chemicals & Small Molecules

Torudokimab (ZB-880) is a monoclonal antibody that neutralizes interleukin 33 and can be used to study immune system diseases and respiratory diseases.

PY314 is a CHO-expressed humanized monoclonal antibody targeting TREM2 with antitumor activity for the study of metastatic renal cell carcinoma.

Izeltabart Tapatansine (IMGC-936) is a CHO-expressing humanized next-generation medetonin-based ADC compound targeting ADAM9-expressing tumors, and exhibits cytotoxicity against ADAM9-positive human tumor cell lines for cancer research.

Anti-Human HN1 Antibody is a monoclonal antibody for use in Flow Cyt and WB.

Busulfan-d8 is a deuterated compound of Busulfan. Busulfan has a CAS number of 55-98-1. Busulfan is a synthetic derivative of dimethane-sulfonate with antineoplastic and cytotoxic properties. Although its mechanism of action is not fully understood, busulfan appears to act through the alkylation of DNA. Following systemic absorption of busulfan, carbonium ions are formed, resulting in DNA alkylation and DNA breaks and inhibition of DNA replication and RNA transcription.

Vancomycin-C13,D3 is a compound labeled with 13C and 2H. Vancomycin is a glycopeptide antibiotic that exerts antibacterial activity by altering cell membrane permeability and selectively inhibiting RNA synthesis.

Vitamin A-d4 is a deuterated compound of Vitamin A. Vitamin A has a CAS number of 68-26-8. Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of CAROTENOIDS found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products.

Isobutyric-d6 acid is a deuterated compound of Isobutyric acid. Isobutyric acid has a CAS number of 79-31-2. Isobutyric acid Description Isobutyric acid is a carboxylic or short chain fatty acid with characteristic sweat-like smell. Small amount of isobutyrate is generated via microbial (gut) metabolism. Small amounts may also be found in certain foods or fermented beverages. There is anosmia (genetic inability to smell) for the odor of isobutyric acid with a frequency of about 2.5%. (OMIM 207000 ). Isobutyric acid is slightly soluble in water but much more soluble in ethanol, ether and organic solvents. Isobutyric acid can affect people if breathed in and may be absorbed through the skin. Contact can irritate and burn the skin and eyes. Breathing Isobutyric acid can irritate the nose, throat and lungs causing coughing, wheezing and/or shortness of breath.

Isovaleric acid-d9 is a deuterated compound of Isovaleric acid. Isovaleric acid has a CAS number of 503-74-2. 3-Methylbutanoic acid is a naturally occurring aroma compound found in Bartlett pear brandies, vanilla beans, rape-honey, and banana.