Romosozumab (AMG-785) is a humanized monoclonal antibody that binds and inhibits sclerostin, increasing bone formation and decreasing bone resorption.Romosozumab is used in the study of postmenopausal osteoporosis.
ASG-5ME is a drug-antibody coupling targeting SLC44A4 that shows anti-tumor activity in xenograft models and may be used to study pancreatic and gastric cancer.
MSC-1 (Anti-LIF Antibody) is a humanized anti-leukemia inhibitory factor (LIF) monoclonal antibody that acquires anti-tumor and pro-inflammatory functions in a homozygous colon cancer mouse model and can be used to study advanced solid tumors.
Ieramilimab (LAG525) is a humanized antibody targeting LAG-3 with potential anticancer activity, blocking its interaction with MHC-II molecules by binding to LAG-3.Pranlukast hemihydrate can be used to study malignant tumors.
Sotigalimab (APX 005) is a monoclonal antibody targeting CD40 with potential antitumor activity and can be used to study metastatic pancreatic cancer and melanoma.