Lipids & Polymers

Tri(Amino-PEG3-amide)-amine, a polyethylene glycol (PEG)-derived linker, is utilized in the synthesis of proteolysis-targeting chimeric molecules (PROTACs)[1].

Tri(Amino-PEG4-amide)-amine is a polyethylene glycol (PEG)-based linker compound used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

UV Cleavable Biotin-PEG2-Azide, a PEG-based PROTAC linker, enables the synthesis of PROTACs[1].

(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthetic E3 ligase ligand-linker conjugate developed for PROTAC technology, comprising the (S,R,S)-AHPC-based VHL ligand and a 5-unit PEG linker [1].

This hetero-bifunctional reagent allows to crosslink alkyne (bio-)molecules to compounds bearing primary amines. The NHS ester group will react with primary amines while the azide can undergo click reaction. This linker is often used to introduce azide moieties into amino-oligonucleotides after solid phase synthesis.

This hetero-bifunctional reagent allows to crosslink alkyne (bio-)molecules to compounds bearing primary amines. The NHS ester group will react with primary amines while the azide can undergo click reaction. This linker is often used to introduce azide moieties into amino-oligonucleotides after solid phase synthesis.

DBCO-PEG3-NHS ester is a degradable ADC linker that can be used to synthesize antibody-coupled active molecules.

Phosphatidylserine (PS) Lipid Microparticles, pHrodoTM Red are beads with attached phosphatidylserine and pHrodoTM Red. Phosphatidylserine (PS) is an anionic, intracellular phospholipid component of the cell membrane and is involved in cell signaling. PS coated microparticles are intended as a positive control for apoptosis or in phagocytosis studies. pHrodo is a trademark of ThermoFisher Scientific.