Lipids & Polymers

Aminooxy-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs [1].

APN-C3-PEG4-azide is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands vital for PROTAC molecule formation. This linker supports selective protein degradation via the cell's ubiquitin-proteasome system.

Azido-PEG3-Val-Cit-PAB-PNP is a cleavable 3-unit PEG ADC linker used for synthesizing antibody-drug conjugates (ADCs) [1] and also functions as a PEG-based PROTAC linker for PROTAC synthesis [2].

Azido-PEG4-Val-Cit-PAB-OH is a 4-unit PEG ADC linker and a PEG-based PROTAC linker used in the synthesis of antibody-drug conjugates (ADCs)[1] and PROTACs[2].

Biotin-PEG2-C4-alkyne, a PEG-based linker for PROTACs, connects two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Biotin-PEG5-amine is a PEG-based PROTAC linker labeled with biotin. It is utilized in the synthesis of PROTACs, a class of molecules with the ability to target and degrade specific proteins[1].

Boc-Aminooxy-PEG2-C2-amine is a polyethylene glycol (PEG)-based linker molecule designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

(S, R, S)-AHPC-PEG4-NH2 hydrochloride is a chemically synthesized conjugate consisting of an E3 ligase ligand-linker, incorporating the VHL ligand based on (S, R, S)-AHPC, and a 4-unit PEG linker, which are specifically designed for use in PROTAC technology.

HO-PEG21-OH is a PEG-based linker for PROTACs, enabling the selective degradation of proteins by connecting two essential ligands and utilizing the ubiquitin-proteasome system within cells.