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    Results for PEG ( 6779 )

      • Ref: BP-24439
        Sizes: 100 MG, 500 MG, 250 MG

        Bromo-PEG12-t-butyl ester is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • Ref: BP-24441
        Sizes: 1 G, 500 MG, 250 MG

        VHL Ligand 1 HCl salt is a synthetic E3 ligase ligand that is useful for PROTAC drug research & discovery. VHL Ligand 1 works by binding the von Hippel-Lindau (VHL) E3 ligase portion of VHL-based PROTACs. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • Ref: BP-24442
        Sizes: 100 MG, 50 MG, 250 MG

        Mal-amido-PEG36-TFP ester is PEG linker containing a maleimide and TFP ester end group. Maleimide groups are reactive with thiols between pH 6.5 and 7.5. The TFP ester can react with primary amine groups and is also less susceptible to undergo hydrolysis compared to NHS ester. The hydrophilic PEG chains increase the water solubility of a compound in aqueous media. Longer PEG chains have improved water solubility relative to shorter PEG chains. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • Ref: BP-24443
        Sizes: 100 MG, 500 MG, 250 MG

        Thalidomide-O-PEG4-t-butyl ester, is synthesized intermediate that incorporatess the Thalidomide based cereblon ligand and PEG space used in PROTAC technology. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • Ref: BP-24444
        Sizes: 100 MG, 50 MG, 250 MG

        TCO-PEG2-TCO is a homebifunctional reagent containing TCO moiety at both ends of the molecule. TCO group specifically and efficiently reacts with tetrazine. The hydrophilic PEG linker increases the solubility of compounds in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • Ref: BP-24445
        Sizes: 1 G, 100 MG, 500 MG, 250 MG

        t-Butoxycarbonyl-PEG2-NHS ester has a t-Boc protecting group and an NHS ester moiety. The t-butyl group can be deprotected under acidic conditions. NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residues or aminosilane-coated surfaces at neutral or slightly basic condition to form a covalent bond. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • Ref: BP-24446
        Sizes: 100 MG, 500 MG, 250 MG

        (S, R, S)-AHPC-PEG4-amine is a PROTAC linker that incorporatess an E3 ligase ligand with a PEG4 unit to empower drug research & discovery. The amine group is reactive with NHS ester or carboxylic acid. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • Ref: BP-24447
        Sizes: 1 G, 100 MG, 500 MG, 250 MG

        Thalidomide-Acid is a linker of Thalidomide which is commonly used as a precursor to PROTAC that hijacks cereblon as the E3 ubiquitin ligase component. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • Ref: BP-24448
        Sizes: 100 MG, 500 MG, 250 MG

        Acid-PEG12-t-butyl ester is a PEG linker containing a t-butyl protected carboxyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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