Results for PEG ( 6779 )
(S, R, S)-AHPC-PEG2-acid is a syntheticPROTAC linker molecule that incorporatess an E3 ligase ligand with a PEG linker to empower PROTAC drug research & discovery. The hydrophilic PEG spacer increases the solubility of a compound in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
Bis-PEG6-TFP ester is a PEG linker with two terminal TFP ester moieties. TFP esters are amine reactive and are also more stable than NHS esters against hydrolysis. The PEG chain increases the water solubility properties of compounds in aqueous media. The water solubility properties of PEG chains are enhanced as the PEG chain grows. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
Desthiobiotin is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd = 1011 vs. 1015 M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin. For pull-down experiments with biological samples, this soft-release characteristic of desthiobiotin also helps to minimize co-purification of endogenous biotinylated molecules, which remain bound to streptavidin upon elution of the target protein complexes with free biotin. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
m-PEG11-CH2COOH is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.