PEG

Thalidomide-O-PEG2-propargyl (E3 Ligase Ligand-Linker Conjugates 32) is a chemical compound that has been synthesized as a conjugate of an E3 ligase ligand and a linker. It incorporates the cereblon ligand based on Thalidomide, along with a 2-unit PEG linker. This compound is specifically designed for use in PROTAC technology, which utilizes ligand-induced protein degradation [1].

Thalidomide-O-PEG4-azide is a PEG-based PROTAC linker utilized in PROTAC synthesis[1].

Thalidomide-O-PEG4-Boc is a PEG-based PROTAC linker utilized in PROTAC synthesis [1].

Thalidomide-O-PEG4-NHS ester is a polyethylene glycol (PEG)-based linker commonly used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Thiol-PEG8-alcohol is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

THP-PEG4-Pyrrolidine(N-Me)-CH2OH, a PEG-based PROTAC linker, aids in the synthesis of PROTAC K-Ras Degrader-1[1].

Tri(Amino-PEG3-amide)-amine, a polyethylene glycol (PEG)-derived linker, is utilized in the synthesis of proteolysis-targeting chimeric molecules (PROTACs)[1].

Tri(Amino-PEG4-amide)-amine is a polyethylene glycol (PEG)-based linker compound used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

UV Cleavable Biotin-PEG2-Azide, a PEG-based PROTAC linker, enables the synthesis of PROTACs[1].