PEG

AEEA-AEEA is a non-cleavable linker used in synthesizing antibody-drug conjugates (ADCs) and alkyl chain-based PROTACs for targeted protein degradation. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

5-ROX (5-Carboxy-X-Rhodamine) is a long wavelength rhodamine dye with high molar absorptivities and high quantum yields. It could be used as a fluorescent dye in nucleic acid related research applications.

Biotin-PEG 3-TFPA serves as a biotinylation reagent featuring a TFP group is easily displaced by amines to rapidly form amides under mild conditions, while biotin is useful for affinity-based applications such as pull-down assays or for ligating with streptavidin proteins. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Biotin-PEG23-Lipoamide is a biotin reagent with lipoic acid, which contains two sulfur atoms (at C6 and C8) connected by a disulfide bond and is thus considered to be oxidized although either sulfur atom can exist in higher oxidation states. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of a biomolecule with a thiol. The biotin group is useful for affinity-based applications. The hydrophilic PEG linker increases the water solubility of the compound. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Biotin-PEG12-DBCO is a biotinylating reagent comprised of DBCO, a click chemistry handle that is frequently used to conjugate with azides on target molecules, and biotin, which is useful for affinity-based applications such as pull-down assays or for ligating with streptavidin proteins. The PEG12 imparts the hydrophilicity of the compound. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Fmoc-Val-Cit-PAB-MMAF serves as an ADC linker with an enzymatically cleavable Val-Cit site. The Val-Cit will specifically be cleaved by Cathepsin B. Fmoc can be deprotected under basic conditions. MMAF is a synthetic antineoplastic agent which may be employed as a cytotoxic payload. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DBCO-PEG-MethylTetrazine, MW 10,000 functions as a clickable PEG polymer possessing methyltetrazine, a terminal TCO reactive group, and DBCO, a click chemistry handle that is frequently used to conjugate with azides on target molecules to form stable triazole linkages. Methyltetrazine can convert azido-containing peptides or proteins into tetrazine-modified peptides or proteins without catalysts or axillary reagents. The hydrophilic PEG chain increases the water solubility of the compound. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DBCO-PEG-MethylTetrazine, MW 5,000 serves as a clickable PEG polymer including methyltetrazine and DBCO, which is frequently used to conjugate with azides on target molecules to form stable triazole linkages. Methyltetrazine reacts with TCO and can convert azido-bearing peptides or proteins into tetrazine-modified peptides or proteins without catalysts or axillary reagents. The 5k polyPEG enhances the hydrophilicity of the compound. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DBCO-PEG-TCO, MW 5,000 is a polyPEG reagent containing TCO, which is a click chemistry handle that readily reacts with tetrazine groups on a target molecule, and DBCO, which is a click chemistry handle that readily reacts with azide groups without the need for copper. The 5k PEG polymer greatly improves the solubility of the compound in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.