PEG

Sulfo-NHS-Acetate, free acid is a water-soluble acylating agent used in protein crosslinking reactions to prevent polymerization. It is also employed to inhibit polymerization when conjugating hapten peptides to carrier proteins for immunogen production.

Bis-propargyl-PEG, MW 20,000 is a crosslinking polyPEG reagent containing two propargyl groups, which enable the formation of triazole linkages with azide-bearing molecules in the presence of copper catalyst. The hydrophilicity of the molecule is improved because of the 20k polyPEG chain.

A bifunctional PEG1000 polymer chain featuring an "click chemistry" azido group and 14 carbon fatty acid tail on each end. This compound may be used for bioconjugation, surface modification, or as a novel component in lipid nanoparticle formulations for mRNA or drug delivery. Reagent grade, for research purpose. Please contact us for GMP-grade.

Methyltetrazine-PEG35-Iodoacetamido represents a special heterobifunctional PEG linker with methyltetrazine, which enables fast click reactions with TCO (trans-cycloctene), and iodoacetamide group, which is an alkylating agent that can be used to bind covalently with the thiol group. The lengthy PEG arm elevates the hydrophilicity of the molecule.

Nonadec-10-enenitrile

Azido-PEG-CH2CO2-NHS, MW 10,000 serves as a bifunctional polyPEG reagent with a terminal azide group which can perform copper-catalyzed Click Chemistry reactions with alkynes, DBCO, and BCN. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The 10k PEG units enhance the water-solubility of the molecule. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

PC Azido-PEG23-OH is a long, photocleavable PEG linker with an azido that can react with alkynes, DBCO, and BCN via copper-catalyzed Click Chemistry reactions. This structure allows for efficient photorelease of linked molecules, typically achieving over 90% cleavage in 5-25 minutes using a near-UV lamp. The PEG polymer bolsters the hydrophilicity of the molecule. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

NH2-PEG-acid, TFA salt, MW 5,000 constitutes a bifunctional PEG polymer consisting of a primary amine that is free to perform a wide variety of reactions such as coupling with carboxylic acids, reductive aminations with ketones or aldehydes, or other more specialized uses. The carboxylic acid can react with primary amine groups in the presence of activators such as HATU. The 5k polyPEG linking the two groups improves the solubility of the molecule in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Lipid 435 is an analog of the ionizable lipid LP01 and features a PEG6-azide linker for click chemistry, bioconjugation, or surface modification applications. This lipid may also be used as a novel component in lipid nanoparticle (LNP) formulations. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.