PEG

t-Boc-N-amido-PEG-CH2COOH, MW 3,400 is a boc-protected PEG-based polymer. Carboxyl can react with primary amine (in the presence of EDC or HATU) via formation of a stable amide bond. The t-Boc can be removed under acidic condition to produce a free amine. Reagent grade, for research purpose.

t-Boc-N-amido-PEG-CH2COOH, MW 2,000 is a t-boc protected PEG reagent with terminal carboxylic acid. Coupling between carboxylic acid (-COOH) and an amine (-NH2) can be done in the presence of activator, such as HATU or EDC, to form a stable amide linkage.The t-boc protecting group can be removed using HCl or TFA to generate a free amine. Reagent grade, for research purpose.

5-azidopentanoic acid

Amino-PEG20-t-butyl ester is a long chain PEG linker containing an amino group with a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DBCO-PEG12-Maleimide is a PEG linker containing a DBCO moiety and a terminal primary maleimide group. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. DBCO is commonly used for copper-free Click Chemistry reactions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

N-(4-Carboxycyclohexylmethyl)maleimide contains a maleimide group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

t-Boc-N-Amido-PEG2-amine is a PEG linker containing an amino group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Tetraethylene glycol is a PEG linker consisting of four ethylene glycol units linked together.

Amino-PEG5-Amine is composed of 5 PEG units with two amino groups. Amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.