S-(5'-Adenosyl)-L-homocysteine (AdoHCys, SAH) is a competitive inhibitor (versus AdoMet) of DNA methyltransferases. AdoHcy is used in a variety of studies on epigenetics in hyperhomocysteinemic states. EC Number: 213-560-8
The fluorogenic PDE substrate FAM-cAMP is used for cAMP-dependent phosphodiesterase assays. It has been used in activity assays for PDE1, PDE2, PDE3, PDE4, PDE7, PDE8, PDE10 and PDE11.
The fluorogenic PDE substrate FAM-cGMP is used for cGMP-dependent phosphodiesterase assays. It has been used in activity assays for PDE5, PDE6 and PDE9.
N-formylkynurenine (Kyn) is an intermediate in the catabolism of
tryptophan by enzymes such as indolamine 2,3-dioxygenases (IDO1 & IDO2) and
tryptophan 2,3-dioxygenase (TDO). It is a formylated derivative of kynurenine and
exhibits an absorption peak at ? = 321 nm.
GC376 a 3CL protease inhibitor is optimized for use with the 3CL Protease (SARS-CoV-2) Assay Kit (BPS Bioscience #79955) and 3CL Protease (SARS-CoV) Assay Kit (BPS Bioscience #78015).
Carbidopa is a decarboxylase inhibitor used in conjunction with levodopa in patients with Parkinson's disease. Carbidopa inhibits the peripheral metabolism of levodopa, which allows a greater proportion of the levodopa to cross the blood - brain barrier for central nervous system effects,