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Activators & Inhibitors

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    Results for Activators & Inhibitors ( 70877 )

      • Quadrol

        Ref: T2206
        Sizes: 1 g, 1 mL * 10 mM (in DMSO)

        Quadrol (Legacy Tebubio ref. 282T2206). Quadrol (EDTP) is an immunostimulant, accelerated wound healing.

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      • CCG-100602

        Ref: T22062
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 1 mL * 10 mM (in DMSO)

        CCG-100602 (Legacy Tebubio ref. 282T22062). CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM).

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      • CHMFL-ABL-053

        Ref: T22067
        Sizes: 25 mg, 100 mg, 50 mg

        CHMFL-ABL-053 (Legacy Tebubio ref. 282T22067). CHMFL-ABL-053 (Compound 18a) is a potent, selective, and orally available inhibitor of BCR-ABL, SRC, and p38 kinases, with IC50 values of 70, 90, and 62 nM against ABL1, SRC, and p38, respectively. CHMFL-ABL-053 is a potentially useful drug candidate for Chronic Myeloid Leukemia (CML) [1].

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      • D-NMAPPD

        Ref: T22069
        Sizes: 1 mg, 5 mg, 50 mg, 10 mg

        D-NMAPPD (Legacy Tebubio ref. 282T22069). D-NMAPPD ((1R,2R)-B13) is an acid ceramidase inhibitor and ceramide analog with potential antiproliferative activity that modulates ceramide signaling in human melanoma cells. D-NMAPPD is used in the study of colon cancer.

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      • Adrenosterone

        Ref: T2207
        Sizes: 50 mg, 1 mL * 10 mM (in DMSO)

        Adrenosterone (Legacy Tebubio ref. 282T2207). Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex.

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      • DBIBB

        Ref: T22070
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 1 mL * 10 mM (in DMSO)

        DBIBB (Legacy Tebubio ref. 282T22070). DBIBB is a non-lipid agonist of specific lysophosphatidic acid (LPA2) type 2 G-protein-coupled receptor. It is a potentially active molecule for the treatment of acute radiation syndrome caused by high intensity gamma rays on hematopoietic and gastrointestinal systems. It is an intermediate in organic synthesis and drug research. DBIBB can be used to prepare various compounds that reduce gastrointestinal radiation syndrome, increase intestinal crypt survival and intestinal cell proliferation, and reduce cell apoptosis.

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      • Eggmanone

        Ref: T22077
        Sizes: 1 mg, 5 mg, 10 mg

        Eggmanone (Legacy Tebubio ref. 282T22077). Eggmanone (EGM1) is a potent, selective phosphodiesterase 4 (PDE4) antagonist, exhibiting an IC50 of 72 nM specifically for PDE4D3. It shows 40- to 50-fold greater selectivity for PDE4D3 over other phosphodiesterases. The mechanism of action involves PDE4 selective antagonism by Eggmanone, which activates protein kinase A, culminating in the blockade of the Hedgehog (Hh) signaling pathway [1].

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      • Bacitracin Zinc

        Ref: T2208
        Sizes: 1 g, 500 mg, 200 mg

        Bacitracin Zinc (Legacy Tebubio ref. 282T2208). Bacitracin Zinc is an antibiotic that interferes with the dephosphorylation of C55-isoprenyl pyrophosphate, interference for inhibition of cleavage of Tyr from Met-enkephalin(IC50=10 μM).

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      • FBPase-1 inhibitor-1

        Ref: T22081
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)

        FBPase-1 inhibitor-1 (Legacy Tebubio ref. 282T22081). FBPase-1 inhibitor-1 (Fructose 1,6-bisphosphatase-1 Inhibitor) is a fructose 1,6-bisphosphatase-1 inhibitor.

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