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Activators & Inhibitors

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    Results for Activators & Inhibitors ( 70877 )

      • ML-031

        Ref: T22101
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg

        ML-031 (Legacy Tebubio ref. 282T22101). ML-031 activated S1P2 with an EC50 value of 1 μM in an S1P reporter assay.

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      • ML-178

        Ref: T22102
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)

        ML-178 (Legacy Tebubio ref. 282T22102). ML-178, a dichlorobenzene, is a potent and selective agonist of sphingosine-1-phosphate receptor 4 (S1PR4), with an EC50 of 46 nM, and has no effect on other S1P receptors at a concentration of 25 μM.

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      • ML-193

        Ref: T22103
        Sizes: 5 mg, 25 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)

        ML-193 (Legacy Tebubio ref. 282T22103). ML-193 (CID 1261822) is a potent and selective GPR55 antagonist (IC50: 221 nM) with over 27-fold selectivity for GPR55 over GPR35, CB1, and CB2. It can ameliorate motor and sensorimotor deficits in Parkinson’s disease (PD) rats.

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      • ML-291

        Ref: T22104
        Sizes: 2 mg

        ML-291 (Legacy Tebubio ref. 282T22104). ML291 is a sufonamidebenzamide compound that induces the unfolded protein response (UPR) and overwhelms the adaptive capacity of UPR, resulting in apoptosis in various solid cancer models. It activates the PERK/eIF2a/CHOP apoptotic pathway of UPR and reduces leukemic cell burden [1].

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      • MLS-573151

        Ref: T22106
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 2 mg, 1 mL * 10 mM (in DMSO)

        MLS-573151 (Legacy Tebubio ref. 282T22106). MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM). It is inactive against other GTPases family members, such as Rab2, Rab7, H-Ras, Rac1, Rac 2 and RhoA wild-type. MLS-573151 acts by blocking the binding of GTP to Cdc42.

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      • Dihydrostreptomycin sulfate

        Ref: T2211
        Sizes: 1 g

        Dihydrostreptomycin sulfate (Legacy Tebubio ref. 282T2211). Dihydrostreptomycin sulfate (Dihydrostreptomycin sesquisulfate) inhibits protein synthesis by binding to the 30S ribosomal subunit. Dihydrostreptomycin Sulfate is a semi-synthetic aminoglycoside antibiotic with bactericidal properties. This antibiotic is active against most gram-positive and gram-negative organisms and is used in the treatment of tuberculosis and tularemia.

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      • NESS 0327

        Ref: T22114
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg

        NESS 0327 (Legacy Tebubio ref. 282T22114). NESS 0327 is a high selectivity antagonist of the cannabinoid CB1 receptor. NESS 0327 is more than 60,000-fold selective for the CB1 receptor.

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      • SM-7368

        Ref: T22115
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 1 mL * 10 mM (in DMSO)

        SM-7368 (Legacy Tebubio ref. 282T22115). The NF-κB Activation Inhibitor III, controls the biological activity of NF-κB. It is primarily used for Inflammation/Immunology applications.

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      • NQTrp

        Ref: T22118
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg

        NQTrp (Legacy Tebubio ref. 282T22118). NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.

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