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Activators & Inhibitors

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    Results for Activators & Inhibitors ( 70877 )

      • NS3694

        Ref: T22119
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)

        NS3694 (Legacy Tebubio ref. 282T22119). NS3694 is an inhibitor of apoptosis and inhibits apoptosome formation and caspase activation.

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      • Geniposide

        Ref: T2212
        Sizes: 100 mg, 1 mL * 10 mM (in DMSO)

        Geniposide (Legacy Tebubio ref. 282T2212). Geniposide is an iridoid glycoside with a variety of biological activities including neuroprotective, anti-diabetic, antiproliferative, and antioxidative activity. Geniposide has been shown to regulate Nrf2 translocation.

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      • Oleoyl Serotonin

        Ref: T22124
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 1 mL * 10 mM (in DMSO)

        Oleoyl Serotonin (Legacy Tebubio ref. 282T22124). Oleoyl Serotonin is an antagonist of hTRPV1 with an IC50 of 2.57 μM.

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      • Org 25543 hydrochloride

        Ref: T22126
        Sizes: 1 mg, 5 mg, 10 mg

        Org 25543 hydrochloride (Legacy Tebubio ref. 282T22126). Org 25543 hydrochloride is a potent and selective glycine transporter type 2 (GlyT2) inhibitor (IC50 = 16 nM for hGlyT2). Displays no activity at GlyT1 or 56 other common biological targets (≥ 100 μM), in a glycine uptake assay in CHO cells.

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      • OU749

        Ref: T22128
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 2 mg, 1 mL * 10 mM (in DMSO)

        OU749 (Legacy Tebubio ref. 282T22128). OU749 is a γ-glutamyl transferase (GGT) inhibitor with an intrinsic Ki of 17.6 μM.

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      • Terconazole

        Ref: T2213
        Sizes: 25 mg, 100 mg, 50 mg, 500 mg, 1 mL * 10 mM (in DMSO)

        Terconazole (Legacy Tebubio ref. 282T2213). Terconazole (Terazol 7) is a synthetic triazole derivative structurally related to fluconazole, antifungal Terconazole seems to disrupt cell wall synthesis by inhibiting biosynthesis of ergosterol or other sterols, damaging the fungal cell membrane, altering its permeability, and promoting loss of essential intracellular elements. Terconazole is active against Candida sp.

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      • PD 166326

        Ref: T22132
        Sizes: 25 mg, 100 mg, 50 mg

        PD 166326 (Legacy Tebubio ref. 282T22132). PD166326, a pyridopyrimidine-type inhibitor of receptor tyrosine kinases, demonstrates antileukemic activity with IC50 values of 6 nM for Src and 8 nM for Abl. [1] [2].

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      • PPIase-Parvulin Inhibitor

        Ref: T22135
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 2 mg

        PPIase-Parvulin Inhibitor (Legacy Tebubio ref. 282T22135). PPIase-Parvulin Inhibitor is a cell-pemeable inhibitor of the Pin1 and Pin4.

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      • PRL-3 Inhibitor I

        Ref: T22136
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 1 mL * 10 mM (in DMSO)

        PRL-3 Inhibitor I (Legacy Tebubio ref. 282T22136). PRL-3 Inhibitor I (BR-1) is a phosphatase of regenerating liver 3 (PRL-3) inhibitor which blocks the migration and invasion of metastatic cancer cells.

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