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Activators & Inhibitors

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    Results for Activators & Inhibitors ( 70877 )

      • TCS HDAC6 20b

        Ref: T22159
        Sizes: 1 mg, 5 mg, 25 mg, 10 mg

        TCS HDAC6 20b (Legacy Tebubio ref. 282T22159). TCS HDAC6 20b (HDAC6-IN-7) is a selective HDAC6 inhibitor that blocks the growth of breast cancer cells and may be used in the study of cancer and neurodegenerative diseases.

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      • Entacapone

        Ref: T2216
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 200 mg, 1 mL * 10 mM (in DMSO)

        Entacapone (Legacy Tebubio ref. 282T2216). Entacapone (OR-611) is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT).

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      • Vialinin A

        Ref: T22168
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg

        Vialinin A (Legacy Tebubio ref. 282T22168). Vialinin A (Terrestrin A), a p-terphenyl compound, exhibits antioxidant properties and acts as a potent inhibitor of TNF-α, USP4, USP5, and sentrin/SUMO-specific protease 1 (SENP1). Its efficacy in autoimmune diseases and cancer research is noteworthy, highlighting its potential therapeutic applications.

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      • Cephalomannine

        Ref: T2217
        Sizes: 20 mg, 1 mL * 10 mM (in DMSO)

        Cephalomannine (Legacy Tebubio ref. 282T2217). Cephalomannine (Baccatin III) is a taxol derivative obtained from Taxus yunnanensis with antitumor activity.

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      • WWL123

        Ref: T22171
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg

        WWL123 (Legacy Tebubio ref. 282T22171). WWL123 is a potent and selective ABHD6 inhibitor (IC50=430 nM). WWL123 crosses the blood-brain-barrier and inhibits ABHD6 in brain parenchyma. ABHD6 blockade by WWL123 exerts an antiepileptic effect in Pentylenetetrazole (PTZ)-induced epileptiform seizures and spontaneous seizures in R6/2 mice.

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      • YS-121

        Ref: T22172
        Sizes: 1 mg, 5 mg, 25 mg, 10 mg

        YS-121 (Legacy Tebubio ref. 282T22172). YS121 is a dual inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1; IC50=3.4 μM) and 5-lipoxygenase (5-LOX; IC50=6.5 μM). YS121 dose-dependently reduces the production of PGE2 with EC50=12 μM in IL-1β-stimulated A549 cells [1].

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      • ZIP (SCRAMBLED) Acetate

        Ref: T22175L
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 2 mg, 1 mL * 10 mM (in DMSO)

        ZIP (SCRAMBLED) Acetate (Legacy Tebubio ref. 282T22175L). ZIP (SCRAMBLED) Acetate (ZIP (SCRAMBLED) Acetate (908012-18-0 Free Base)) is a scrambled peptide that can be used as a negative control for zeta inhibitory peptide (ZIP).

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      • Spadin Acetate

        Ref: T22178L
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 2 mg, 1 mL * 10 mM (in DMSO)

        Spadin Acetate (Legacy Tebubio ref. 282T22178L). Spadin Acetate is a natural peptide derived from a propeptide released in blood. Spadin Acetate is able to block the TREK-1 channel activity. Spadin Acetate binds specifically to TREK-1 with an affinity of 10 nM.

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      • 8-Azaguanine

        Ref: T2218
        Sizes: 100 mg, 50 mg, 500 mg, 200 mg

        8-Azaguanine (Legacy Tebubio ref. 282T2218). 8-Azaguanine (SK 1150) is a purine analogue with potential antineoplastic activity.

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