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Activators & Inhibitors

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    Results for Activators & Inhibitors ( 70877 )

      • 2-Methoxyestradiol

        Ref: T2220
        Sizes: 25 mg, 100 mg, 50 mg, 200 mg, 1 mL * 10 mM (in DMSO)

        2-Methoxyestradiol (Legacy Tebubio ref. 282T2220). 2-Methoxyestradiol (2-ME2) is an orally bioavailable estradiol metabolite with potential antineoplastic activity. 2-Methoxyestradiol inhibits angiogenesis by reducing endothelial cell proliferation and inducing endothelial cell apoptosis. This agent also inhibits tumor cell growth by binding to tubulin, resulting in antimitotic activity, and by inducing caspase activation, resulting in cell cycle arrest in the G2 phase, DNA fragmentation, and apoptosis.

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      • iMAC2

        Ref: T22202
        Sizes: 25 mg, 100 mg, 50 mg

        iMAC2 (Legacy Tebubio ref. 282T22202). iMAC2, a potent MAC (Membrane Attack Complex) inhibitor, exhibits an IC50 of 28 nM and an LD50 of 15,000 nM, demonstrating significant efficacy in inhibiting MAC. Additionally, iMAC2 effectively suppresses apoptosis by blocking the release of cytochrome c [1].

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      • LY 2389575 hydrochloride

        Ref: T22204
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg

        LY 2389575 hydrochloride (Legacy Tebubio ref. 282T22204). LY2389575 hydrochloride is an mGlu3 negative allosteric modulator (NAM) that is selective and non-competitive, with an IC50 value of 190 nM. LY2389575 hydrochloride induces an increase in the level of Mrc1, which amplifies the toxicity of β-amyloid (Aβ), and can be used to study Alzheimer's disease. It can be used to study Alzheimer's disease.

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      • Uridine

        Ref: T2221
        Sizes: 100 mg, 500 mg, 1 mL * 10 mM (in DMSO)

        Uridine (Legacy Tebubio ref. 282T2221). Uridine (Uridin) is a nucleoside compound, one of the four bases that make up RNA, that replaces thymine in DNA during transcription and pairs with adenine.

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      • 1,5,5-Trimethylhydantoin

        Ref: T22214
        Sizes: 1 g, 500 mg, 200 mg, 1 mL * 10 mM (in DMSO)

        1,5,5-Trimethylhydantoin (Legacy Tebubio ref. 282T22214). 1,5,5-Trimethylhydantoin (TMH) serves as a non-isotopic internal standard (IS).

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      • 1-Naphthyl phosphate potassium salt

        Ref: T22215
        Sizes: 25 mg, 50 mg, 10 mg, 1 mL * 10 mM (in DMSO)

        1-Naphthyl phosphate potassium salt (Legacy Tebubio ref. 282T22215). 1-Naphthyl phosphate potassium salt inhibits non-specific phosphatase.

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      • 10-Undecen-1-ol

        Ref: T22216
        Sizes: 10 g, 5 g, 1 mL * 10 mM (in DMSO)

        10-Undecen-1-ol (Legacy Tebubio ref. 282T22216). 10-Undecen-1-ol is converted from ricinoleic acid. 10-Undecen-1-ol can be used as a comonomer for the introduction of functional groups[1][2].

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      • 2'-Deoxyguanosine

        Ref: T22218
        Sizes: 500 mg, 1 mL * 10 mM (in DMSO)

        2'-Deoxyguanosine (Legacy Tebubio ref. 282T22218). 2'-Deoxyguanosine (Guanine deoxyriboside) is a purine nucleoside that is recognized by members of the 2'-dG-II family.2'-Deoxyguanosine has been associated with aging, mutation, and carcinogenesis, and is oxidized by molecular oxygen.

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      • Carbinoxamine Maleate Salt

        Ref: T2222
        Sizes: 25 mg, 100 mg, 50 mg, 500 mg, 200 mg, 1 mL * 10 mM (in DMSO)

        Carbinoxamine Maleate Salt (Legacy Tebubio ref. 282T2222). Carbinoxamine Maleate Salt (Lergefin) is an ethanolamine class of H1 antihistamines with mild antimuscarinic and sedative properties.

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