Lipids & Polymers

Pomalidomide-PEG4-C2-NH2 hydrochloride (Legacy Tebubio ref. 282T40032). Pomalidomide-PEG4-C2-NH2 hydrochloride is a PEG-based PROTAC linker used for synthesizing PROTACs[1].

Thalidomide-NH-PEG4-COOH (Legacy Tebubio ref. 282T40036). Thalidomide-NH-PEG4-COOH is a conjugate comprising an E3 ligase ligand-linker, utilized in the synthesis of dCBP-1. dCBP-1 itself functions as a powerful and selective heterobifunctional degrader targeting p300/CBP.

A 410099.1 amide-PEG2-amine-Boc (Legacy Tebubio ref. 282T40052). A 410099.1 amide-PEG2-amine-Boc is a functionalized IAP ligand for PROTACs, combining an IAP ligand with an amide-PEG3 linker terminating in an amine, facilitating the formation of conjugates with target protein ligands.

A 410099.1 amide-PEG3-amine-Boc (Legacy Tebubio ref. 282T40054). A 410099.1 amide-PEG3-amine-Boc is an IAP ligand-based functionalized molecule commonly used in PROTACs, consisting of an IAP ligand and an amide-PEG3 linker with a terminal amine. The compound effectively conjugates with target protein ligands.

Pomalidomide-amino-PEG5-NH2 hydrochloride (Legacy Tebubio ref. 282T40085). Pomalidomide-amino-PEG5-NH2 hydrochloride is a synthesized chemical compound that functions as an E3 ligase ligand-linker conjugate, combining a Pomalidomide-based cereblon ligand with a linker commonly used in PROTAC technology.

Pomalidomide-PEG3-C2-NH2 hydrochloride (Legacy Tebubio ref. 282T40105). Pomalidomide-PEG3-C2-NH2 hydrochloride, also known as Cereblon Ligand-Linker Conjugate 5, is a chemically synthesized E3 ligase ligand-linker conjugate. This compound incorporates a cereblon ligand based on Pomalidomide and a linker commonly employed in PROTAC technology.

Azido-PEG2-C6-Cl (Legacy Tebubio ref. 282T40201). Azido-PEG2-C6-Cl is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.

AZD-CO-Ph-PEG4-Ph-CO-AZD (Legacy Tebubio ref. 282T40203). AZD-CO-Ph-PEG4-Ph-CO-AZD is a bis-β-lactam linker frequently used in the synthesis of antibody-siRNA conjugates.

PEG-8 laurate (Legacy Tebubio ref. 282T40438). PEG-8 laurate is a monofunctional surfactant and skin penetration enhancer. It disrupts the skin barrier and facilitates the formation of elastic vesicles when synthesized.