Lipids & Polymers

Thalidomide-O-acetamido-C4-amine HCl salt comprises a Thalidomide based cereblon ligand and a ligand-linker conjugate. This E3 ligase ligand-linker conjugate is used in PROTAC technology. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Pomalidomide 4'-PEG3-azide is an E3 ligase ligand-linker that incorporatess the Pomalidomide-based cereblon ligand and a linker. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

P131 is a PROTAC molecule comprised of Pomalidomide-based cereblon ligand and IBT6A, linked by a PEG 3 chain. P131 was initial developed by Sun (2018) that can degrade both wild-type and C481S mutant BTK with nanomolar potencies. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

(S, R, S)-AHPC-PEG3-amine hydrochloride salt comprises VHL Ligand coupled to an amine via a PEG3 linker. The VHL Ligand 1 is a synthetic compound used in PROTAC research based on E3 ligase ligand. NH2 group is reactive with carboxylic acids in the presence of coupling reagent such as EDC, or directly with NHS esters, to form a stable amide bond. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

3-[2-(3-hydroxypropoxy)ethoxy]propan-1-ol is a linker consisting of two terminal hydroxyl groups. The partial PEG chain increases the water solubility of a compound in aqueous media. The hydroxyl groups enables further derivatization or replacement with other reactive functional groups.

1,4-Di(3-Hydroxypropoxy)butane is a linker consisting of two terminal hydroxyl groups. The hydroxyl groups enables further derivatization or replacement with other reactive functional groups.

HO-PPG1-PEG2-PPG1-OH is a linker consisting of two terminal hydroxyl groups. The partial PEG chain increases the water solubility of a compound in aqueous media. The hydroxyl groups enables further derivatization or replacement with other reactive functional groups.

TCEP, Hydrochloride salt is a reducing agent used in biology and biochemistry and applications.

m-PEG4-TCO is commonly used in Click Chemistry reactions.