Lipids & Polymers

TCO-PEG12-TCO is a PEG reagent containing TCO moiety at both ends of the molecule. TCO group specifically and efficiently reacts with tetrazine. The hydrophilic PEG12 arm increases the solubility of compounds in aqueous media. Reagent grade, for research use only.

N-(Acid-PEG36-PEG3-)-N-bis(PEG3-biotin) is a branched biotin linker that can be used for protein labeling. The carboxylic acid group can react with primary amines in the presence of activators such as EDC and HATU. The hydrophilic PEG branch increases the water solubility of the compound. Reagent grade, for research use only.

3-Hydroxy-2-(hydroxymethyl)propyl 6-bromohexanoate is a branched PEG linker with bromine and hydroxyl moieties. The alcohol groups can react to further derivatize the compound. The bromine (Br) is a very good leaving group for nucleophilic substitution reactions. Reagent grade, for research use only.

Amino-PEG12-amine is a conjugation linker containing two amine (NH2) groups. The hydrophilic PEG spacer increases solubility in aqueous media. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde), etc. Reagent grade, for research use only.

DSPE-PEG13-NHS is a PEG linker containing DSPE and amine moieties. The hydrophobic properties of the DSPE allow for the encapsulation and congregation of other hydrophobic drugs. The hydrophilic PEG linker increases the water solubility of the overall compound allowing for the delivery of the drug. The amine group is reactive with NHS ester at pH 6.5-7.5 to form a covalent amide bond. Reagent grade, for research use only.

DSPE-PEG8-amido-DBCO is a PEG linker containing DSPE and DBCO moieties. The hydrophobic properties of the DSPE allow for the encapsulation and congregation of other hydrophobic drugs. The hydrophilic PEG linker increases the water solubility of the overall compound allowing for the delivery of the drug. The DBCO group can be used for copper-free Click Chemistry reactions. Reagent grade, for research use only.

t-Boc-Aminooxy-PEG7-Mal contains a Boc-protected aminooxy group and a terminal maleimide group. The maleimide group will react with a thiol group to form a covalent bond. The hydrophilic PEG spacer increases solubility in aqueous media. The Boc-protected amine can be deprotected under mild acidic conditions. Reagent grade, for research use only.

Benzyl-PEG13-alcohol is a PEG linker with a benzyl protecting group and a reactive primary alcohol. The primary alcohol can react and further derivatize the compound. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. The benzyl group can be removed under catalytic hydrogenation conditions to give free hydroxyl for derivitazation. Reagent grade, for research use only.

N-Desthiobiotin-N-bis(PEG4-Acid) is a PEG linker containing two carboxylic acid groups and desthiobiotin, which is a modified form of biotin that binds to avidin, streptavidin and other biotin-binding protein-based affinity columns are recognized by anti-biotin antibodies. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. HATU). Reagent grade, for research use only.