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Lipids & Polymers

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    Results for Lipids & Polymers ( 10111 )

      • BP Lipid 309

        Ref: BP-40124
        Sizes: 100 MG, 50 MG, 250 MG

        BP Lipid 309 is an ionizable lipid analogue of ALC-0315 featuring a tertiary amine head, a central tertiary amine, and two identical esters linking to nonpolar tails. Ionizable lipids such as this may be applied in the development of lipid nanoparticles for drug delivery. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • D-Lin-MC2-DMA

        Ref: BP-40125
        Sizes: 25 MG, 100 MG, 50 MG, 250 MG

        D-Lin-MC2-DMA is a synthetic ionizable lipid that is frequently used in combination with other lipids in the development of lipid nanoparticles for drug delivery.

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      • D-Lin-MC4-DMA

        Ref: BP-40126
        Sizes: 25 MG, 100 MG, 50 MG, 250 MG

        D-Lin-MC4-DMA is a synthetic ionizable lipid that is frequently used in combination with other lipids in the development of lipid nanoparticles for drug delivery.

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      • D-lin-MeOH

        Ref: BP-40127
        Sizes: 100 MG

        D-lin-MeOH is a prevalent component of lipids used in LNP development such as the D-Lin-MC3-DMA family.

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      • Boc-O-SN-38

        Ref: BP-40130
        Sizes: 1 G, 100 MG, 500 MG, 250 MG

        Boc-O-SN-38 is a derivative of SN-38, an anti-tumor payload that is often linked to ADCs to be directly delivered to cells. Its mechanism of action is inhibition of DNA topoisomerase I, halting DNA synthesis and causing single-strand breaks in DNA. The Boc protection allows for controlled reactions without affecting the amine functionality.

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      • Diethylene glycol monopentyl ether

        Ref: BP-40131
        Sizes: 1 G, 500 MG

        Diethylene glycol monopentyl ether is a hybrid PEG linker featuring an aliphatic pentyl tail and a primary alcohol.

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      • t-Boc-N-amido-PEG18-amine

        Ref: BP-40132
        Sizes: 100 MG, 500 MG, 250 MG

        t-Boc-N-amido-PEG18-amine is a bifunctional PEG linker consisting of a Boc-protected amine and an amine. The amine is reactive with carboxylic acids or activated esters, while the Boc can be deprotected with strong acid.

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      • t-Boc-N-amido-PEG20-amine

        Ref: BP-40133
        Sizes: 100 MG, 500 MG, 250 MG

        t-Boc-N-amido-PEG20-amine is a bifunctional PEG linker consisting of a Boc-protected amine and a free amine. The amine is reactive with carboxylic acids or activated esters, while the Boc can be deprotected with strong acid.

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      • NH-bis(PEG8-t-butyl ester)

        Ref: BP-40134
        Sizes: 1 G, 100 MG, 500 MG, 250 MG

        NH-bis(PEG8-t-butyl ester) is a bifunctional PEG linker with a pair of t-butyl esters joined together at a secondary amine. The secondary amine can be used as a nucleophile while the t-butyl esters can be deprotected to allow for reactions with nucleophiles such as amines or alcohols. The use of a PEG spacer increases aqueous solubility and will impact the ADME of the final PEG conjugate.

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