Lipids & Polymers

Desthiobiotin-PEG3-Amine is a short PEG linker featuring a primary amine and a desthiobiotin group. Primary amines readily form amides with carboxylic acids in the presence of coupling reagents such as HATU or EDC. Desthiobiotin is used for affinity-based applications such as pull-down assays or for ligating with streptavidin proteins.

BP Lipid 801 is an ionizable amino lipid featuring an ethanolamine headgroup with a tertiary amine and two ester branches. A compound like this may be employed in the development of lipid nanoparticles for drug delivery. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Azide-PEG8-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane is a multifunctional reagent containing an azide and three t-butyl esters. The azide is reactive with terminal alkynes, DBCO, BCN for click chemistry. The t-butyl esters can be deprotected and subsequently reacted with primary amine groups to form stable amide bonds.

JQ1 carboxylic acid serves as a potent BET bromodomain inhibitor. It features a carboxylic acid functional group, making it suitable for conjugation reactions.

DSPE-PEG-Fluor 555, MW 2,000 is a PEG lipid conjugate with a DSPE group and a Fluor 555 dye. Fluor 555 is a bright orange cyanine-based dye while DSPE is a phospholipid frequently employed in the development of lipid nanoparticles.

t-Boc-N-Amido-PEG8-Ms is a heterobifunctional PEG linker featuring a Boc-protected amine and a mesylate group. Mesylates are a good leaving groups which are readily displaced by nucleophiles while the Boc protecting group can be removed with acid to reveal an amine which can be used in a variety of chemical transformations.

Biotin-PEG4-Amide-PEG8-Amine is a PEG linker featuring a primary amine and a biotin group. Primary amines readily form amides with carboxylic acids in the presence of coupling reagents such as HATU or EDC. Biotin is used for affinity-based applications such as pull-down assays or for ligating with avidin proteins.

DSPE-Amide-PEG-Rhodamine, MW 2,000 is a PEG lipid with a DSPE group and a Rhodamine fluorophore. DSPE is a phospholipid that is known to spontaneously form micelles in water and is featured heavily in lipid nanoparticles and drug development. Rhodamine is a fluorescent dye with excitation and emission maxima at 570 and 595 nm respectively.

3-Hydroxy-2-(hydroxymethyl)propyl (9Z)-9-hexadecenoate is a lipid intermediate featuring a palmitoleate ester linked to a branched central carbon with two free primary alcohols. A compound like this may be employed in the development of lipid nanoparticles for drug delivery.