Nucleotides

3'-F-3'-dG(iBu)-2'-phosphoramidite is a purine nucleoside amidite analog that can be subjected to facilitate the making of DNA or RNA.

5-Formylindole-CE Phosphoramidite is a versatile aldehyde modifier that facilitates electrophilic substitution in oligonucleotides by reacting with amino groups to form Schiff's bases, hydrazino groups to create hydrazones, and semicarbazides to generate semicarbazones, enhancing their functionality.

The DMTr-LNA-G(iBu)-3'-CED-phosphoramidite is a pivotal component in Locked Nucleic Acid (LNA) oligonucleotide synthesis. It features a ribonucleoside connected through a methylene unit between the 2’-oxygen and 4’-carbon atoms, mirroring DNA polymer synthesis.

DMTr-LNA-A(Bz)-3-CED-phosphoramidite is a Locked Nucleic Acid (LNA) phosphoramidite, which is a bicyclic amidite where a ribonucleoside is linked between the 2’-oxygen and the 4’-carbon atoms with a methylene unit.

1-[(5E)-3-O-[(Bis-diiPr-amino)(2-cyano ethoxy)phosphino]-5,6-dideoxy-6-(diethoxy phosphinyl)-2-O-(2-MeO-Et)-?-D-ribo-hex-5-enofuranosyl]uracil, containing a 2'-O-MOE-modified uridine nucleoside, can be used to form antisense RNA. The 2'-MOE backbone enhances duplex stability and nuclease protection.

DMTr-LNA-5MeC(Bz)-3-CED-phosphoramidite is a Locked Nucleic Acid (LNA) phosphoramidite, which is a bicyclic amidite where a ribonucleoside is linked between the 2’-oxygen and the 4’-carbon atoms with a methylene unit. This amidite is integral to Locked Nucleic Acid (LNA) oligonucleotide synthesis, following a parallel process to DNA polymers.

DMTr-LNA-5MeU-3-CED-phosphoramidite is vital for Locked Nucleic Acid (LNA) oligonucleotide synthesis, which features a ribonucleoside connected by a methylene unit between 2’-oxygen and 4’-carbon atoms, mirroring DNA polymerization in structure and process.

DMTr-LNA-U-3-CED-phosphoramidite is a component essential to Locked Nucleic Acid (LNA) oligonucleotide synthesis, which entails the incorporation of a ribonucleoside linked by a methylene unit between the 2’-oxygen and 4’-carbon atoms, mirroring DNA polymerization.

3'-O-MOE-A(Bz)-2'-CED-phosphoramidite is a phosphoramidite monomer for crafting unique oligonucleotides or modified RNA derivatives.