Nucleotides

2'-OMe-G(iBu)-3'-phosphoramidite is a chemically unstable and heat-sensitive nucleoside phosphoramidite that serves as a foundational element in oligonucleotide synthesis.

2'-O-Propargyl G(iBu)-3'-phosphoramidite, containing propargyl and benzoyl groups, readily attaches to diverse biomolecules. Through click chemistry, its reactive propargyl unit conjugates with azide-linked compounds, enabling versatile molecular binding for conjugation.

2'-O-Propargyl A(Bz)-3'-phosphoramidite includes exceptional propargyl and benzoyl functionalities that allow it to easily bind to a wide range of biomolecules. The propargyl unit, utilizing click chemistry, reacts with azide molecules for conjugation purposes.

5'-O-DMTr-5-iodo-2'-dU-3'-CED is a synthetic nucleoside phosphoramidite utilized to integrate iodo-modified deoxyuridine within an oligonucleotide, either internally or at the 5' end.

14-(Amide-PEG4-ethylcarbamoyl)tridecanoic t-butyl ester has an amine group on a PEG linker with a alkane tail that has a t-butyl ester group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl group can be deprotected under acidic conditions. This compound may also be used as a building block for lipids in nanotechnolgy and drug delivery. Reagent grade, for research purpose.

VIC is an asymmetrical xanthene dye (two flanking rings are not the same). This dye is used for the design of qPCR probes. The spectral properties of VIC are similar to HEX and JOE.

DusQ 1 is a fluorescence quencher with the most effective absorption in the range of 480–580 nm, the maximum absorption is at 534 nm.

DusQ 1 dT phosphoramidite is a nucleoside amidite used in oligonucleotide synthesis. It features a true dark quencher nucleotide base, which is commonly employed for internal labeling of DNA oligonucleotide probes. The reagent includes DMT protection for the hydroxymethyl group, enabling effective purification of oligonucleotides using cartridges.

DusQ 1 phosphoramidite is a true dark quencher with broad absorption curve which covers the visible spectrum with maximum in green to yellow region. It is used for the synthesis of dual labeled oligonucleotide probes for qPCR bearing 5'-quencher DusQ 1 and other FRET applications for multiplexing assays.