Peptides & Amino Acids

Akt is a serine/threonine kinase that enhances cell proliferation and inhibits apoptosis when activated. Akt associates with PI(3,4,5)P3) at the cell membrane through its pleckstrin homology domain and is activated through phosphorylation. 3-Phosphoinositide-dependent kinase-1 (PDK1) has been shown to first phosphorylate Akt at Thr308, then a second kinase phosphorylates Akt at position Ser473. In turn, Akt phosphorylates a host of proteins including the proapoptotic proteins BAD and pro-caspase-9, GSK3, p21WAF1, MDM2, and the forkhead (FKHR) family of transcription factors.

NFkB p65 phospho S276 peptide for use in control assays with purified antibodies Anti-NFkB p65 pS279 (p/n 100-401-264 and 600-401-264). Also available NFkB p65 non-phospho S276 peptide (p/n 000-000-264NP).

NFkB p65 non-phospho S276 peptide for use in control assays with purified antibodies Anti-NFkB p65 pS279 (p/n 100-401-264 and 600-401-264). Also available NFkB p65 phospho S276 peptide (p/n 000-000-264).

NFkB p65 phospho S529 peptide for use in control assays with purified antibodies Anti-NFkB p65 pS529 (p/n 100-401-266). Also available NFkB p65 non-phospho S529 peptide (p/n 000-000-266NP).

NFkB p65 non-phospho S529 peptide for use in control assays with purified antibodies Anti-NFkB p65 pS529 (p/n 100-401-266). Also available NFkB p65 phospho S529 peptide (p/n 000-000-266).

ATM non-phospho S1981 peptide for use in control assays with purified antibody Anti-ATM S1981 non-phospho (p/n 600-401-398). Also available ATM phospho S1981 peptide (p/n 000-000-400) and Anti-ATM pS1981 phospho antibodies (p/n 200-301-400 and 600-601-400).

ATM phospho S1981 peptide for use in control assays with purified antibodies Anti-ATM pS1981 (p/n 200-301-400 and 600-601-400). Also available ATM non-phospho S1981 peptide (p/n 000-000-398) and Anti-ATM non-phospho S1981 (p/n 600-401-398).