Cell Line

Please note this product may be subject to fees, we invite you to contact your local office. HER3 CHO Cell Line is a CHO-K1 cell line expressing HER3 (human epidermal growth factor receptor 3) (NM_001982.2, also known as receptor tyrosine-protein kinase erbB-3) under the control of a cytomegalovirus (CMV) promoter. This cell line was generated by lipid-mediated transfection followed by hygromycin selection and limited dilution. Individual clones were screened for HER3 expression levels by flow cytometry, and a clone was selected to generate this cell line.

Please note this product may be subject to fees, we invite you to contact your local office. The TSLP Responsive Luciferase Reporter Ba/F3 Cell Line is a murine Ba/F3 cell line engineered to express both TSLP-R (thymic stromal lymphopoietin receptor, also known as CRLF2, cytokine receptor like factor 2) (NM_022148.4) and IL-7Ra (Interleukin 7 receptor alpha) (NM_002185.5) separated by a self-cleaving P2A peptide. The construct was delivered bytransduction of STAT5 Luciferase Reporter Ba/F3 cells (#79772), which express a firefly luciferase reporter driven by STAT5 response elements located upstream of the minimal TATA promoter. After activation by TSLP, the endogenous transcription factor STAT5 binds to the response elements, inducing transcription of the luciferase reporter gene. This cell line has been validated to respond to TSLP. Additional functional validation demonstrates that TSLP-induced luciferase activity can be inhibited by either anti-TSLP or anti-TSLPR neutralizing antibo

Female. Age: Adult. Ethnicity: Epithelial. Disease: Thyroid gland papillary carcinoma. Please note this product may be subject to fees, we invite you to contact your local office.

Please note this product may be subject to fees, we invite you to contact your local office. eGFP/Firefly Luciferase THP-1 Cell Line is a THP-1 cell line expressing firefly luciferase and enhanced GFP (eGFP) driven by an EF1a promoter. The cells were generated by transduction with Firefly Luciferase-eGFP lentivirus (BPS Bioscience #78741), which is a SIN (self-inactivating) lentivirus.

Please note this product may be subject to fees, we invite you to contact your local office. MART-1 TCR (DMF5) CD8⁺NFAT-Luciferase Reporter Jurkat Cell Line is a Jurkat cell line generated from the T Cell Receptor (TCR) Knockout NFAT Luciferase Reporter Jurkat Cell Line (BPS Bioscience #78556) by overexpression of human CD8 (NM_001768.6) and MART-1-specific TCR (DMF5) using lentiviral transduction (with CD8a Lentivirus #78648 and MART-1-Specific TCR Lentivirus (Clone DMF5) #78679). The human TCR clone DMF5 specifically recognizes tumor antigen MART-1 (Melanoma-associated antigen recognized by T cells-1, or Melan-A).

Please note this product may be subject to fees, we invite you to contact your local office. MAGE-A1 CD8⁺ NFAT-Luciferase Reporter Jurkat Cell Line was generated from T Cell Receptor (TCR) Knockout NFAT Luciferase Reporter Jurkat Cell Line (BPS Bioscience #78556) by overexpression of human CD8 (NM_001768.6) and MAGE-A1 (Melanoma-associated antigen 1) TCR using lentiviral transduction (with CD8a Lentivirus #78648 and MAGE-A1-Specific TCR Lentivirus #78934). This human MAGE-A1 TCR specifically recognizes antigen MAGE-A1 peptide, amino acids 278-286 (KVLEYVIKV). <img src="{{media url="wysiwyg/82304-1.png"}}" alt="" width="531" height="306" /> Figure 1: Illustration of the functional co-culture assay used to validate the MAGE-A1 TCR CD8⁺ NFAT-Luciferase Reporter Jurkat Cell Line.  

Please note this product may be subject to fees, we invite you to contact your local office. ADAR1 Activity TWO-Luciferase Reporter HEK293 Cell Line is a HEK293 cell line designed to monitor cell viability in parallel with ADAR1 (adenosine deaminase acting on RNA) enzyme activity. These cells were engineered to express ADAR1 (NM_001111.5) and an ADAR1 reporter construct. This construct is comprised of an ADAR1 hairpin target with a stop codon (UAG) susceptible to ADAR1-mediated editing to tryptophan (UUG), located upstream of a firefly luciferase reporter. In addition, they constitutively express Renilla Luciferase under the control of a CMV promoter, which can be used to determine cell viability. This cell line has been validated by treatment with ADAR1 siRNA and the ADAR1 inhibitor Fludarabine. The ADAR1 reporter construct is comprised of an ADAR1 hairpin target with a stop codon (UAG) upstream of the sequence encoding firefly luciferase. In the absence of ADAR1, firefly luciferase i

Please note this product may be subject to fees, we invite you to contact your local office. KRAS G12D TCR (Clone 10) CD8⁺ NFAT-Luciferase Reporter Jurkat Cell Line was generated from T Cell Receptor (TCR) Knockout NFAT Luciferase Reporter Jurkat Cell Line (BPS Bioscience #78556) by overexpression of human CD8 (NM_001768.6) and KRAS (Kirsten sat sarcoma virus) G12D TCR (Clone 10) using lentiviral transduction (with CD8a Lentivirus  #78648 and KRAS G12D Specific TCR Lentivirus (Clone 10) #78937). This TCR specifically recognizes the antigen KRAS G12D Peptide, amino acids 10-19 (GADGVGKSAL, 10mer). Purchase of this cell line is for research purposes only; commercial use requires a separate license. View the full terms and conditions.

Please note this product may be subject to fees, we invite you to contact your local office. KRAS G12D TCR (Clone 10) CD8⁺ NFAT-Luciferase Reporter Jurkat Cell Line was generated from T Cell Receptor (TCR) Knockout NFAT Luciferase Reporter Jurkat Cell Line (BPS Bioscience #78556) by overexpression of human CD8 (NM_001768.6) and KRAS (Kirsten sat sarcoma virus) G12D TCR (Clone 10) using lentiviral transduction (with CD8a Lentivirus  #78648 and KRAS G12D Specific TCR Lentivirus (Clone 10) #78937). This TCR specifically recognizes the antigen KRAS G12D Peptide, amino acids 10-19 (GADGVGKSAL, 10mer). Purchase of this cell line is for research purposes only; commercial use requires a separate license. View the full terms and conditions.