Results for Chemicals & Small Molecules ( 98424 )
Hydroxyzine dihydrochloride-d4 is a deuterated compound of Hydroxyzine dihydrochloride. Hydroxyzine dihydrochloride has a CAS number of 2192-20-3. Hydroxyzine hydrochloride is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
Iguratimod-d5 is a deuterated compound of Iguratimod. Iguratimod has a CAS number of 123663-49-0. Iguratimod is an antirheumatic agent, acts as an inhibitor of COX-2, with an IC50 of 20 μM (7.7 μg/mL), but shows no effect on COX-1. Iguratimod also inhibits macrophage migration inhibitory factor (MIF) with an IC50 of 6.81 μM.
Indobufen-d5 is a deuterated compound of Indobufen. Indobufen has a CAS number of 63610-08-2. Indobufen is an inhibitor of platelet aggregation and is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A2 (TxA2) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes.