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Chemicals & Small Molecules

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    Results for Chemicals & Small Molecules ( 98424 )

      • Suc-AEPF-AMC

        Ref: TP2509
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg

        Suc-AEPF-AMC (Suc-Ala-Glu-Pro-Phe-AMC) is a peptide substrate for the peptidyl prolyl isomerases Pin1 and Par14, and is a peptide compound that can be used to assay protease activity.

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      • DRF-1042 HCl

        Ref: T15168L
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg

        DRF-1042 HCl is an orally active camptothecin analog with antitumor activity, inhibits DNA topoisomerase I, and is used in the study of refractory solid tumors.

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      • Fluorescein-DBCO

        Ref: T15290
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 10 mg

        Fluorescein-DBCO is a non-cleavable linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

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      • L-Palmitoylcarnitine

        Ref: T15698
        Sizes: 1 mg, 5 mg, 10 mg

        L-Palmitoylcarnitine (L-PC) is an important endogenous fatty acid metabolite that inhibits Na/K ATPase activity and potentiates fibrinolytic enzymes and tPA to inhibit thrombosis.

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      • Sulfo-NHS-Acetate

        Ref: T16959
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg

        Sulfo-NHS-Acetate, an alkyl chain-derived PROTAC linker, is utilized for synthesizing PROTACs[1].

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      • 3',4',5',5,7-Pentamethoxyflavanone

        Ref: T1729
        Sizes: 1 mg, 5 mg, 25 mg, 10 mg

        3',4',5',5,7-Pentamethoxyflavanone is a natural flavonoid compound found in [Neoraptua magnifica var. magnifica].

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      • DADPS Biotin Azide

        Ref: T17582
        Sizes: 1 mg, 5 mg, 25 mg, 10 mg

        Biotin-PEG4-amino-t-Bu-DADPS-C6-azide is a PEGylated PROTAC linker suitable for PROTAC synthesis [1].

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      • MC-Val-Cit-PAB-MMAF

        Ref: T18326
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg

        MC-Val-Cit-PAB-MMAF is an antibody-drug conjugate (ADC) component that exhibits antitumor properties through the action of the tubulin inhibitor, monomethyl auristatin F (MMAF), which is connected by a cathepsin-cleavable linker, MC-Val-Cit-PAB.

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      • Vc-seco-DUBA

        Ref: T18362
        Sizes: 1 mg, 5 mg

        Vc-seco-DUBA is a drug-linker conjugate for ADC with potent antitumor activity by using DUBA (DNA alkylating agent), linked via the ADC linker Vc-seco[1].

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