Chemicals & Small Molecules

N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) is a modified nucleotide that minimizes immunogenicity and enhances stability to improve mRNA synthesis.

Glycolithocholic acid 3-sulfate (SLCG), a cholic acid derivative and glycolithocholic acid metabolite, effectively inhibits HIV-1 replication in vitro. This compound holds potential for researching HIV infection and gallbladder disease [1] [2].

Normetanephrine, an endogenous metabolite found in cerebrospinal fluid, has applications in hypertension research [1] [2].

Geranyl diphosphate (Geranyl pyrophosphate) is an isoprenoid, an intermediate in the synthesis of cannabinoids, and a substrate for the manufacture of volatile monoterpenes, which can be used by plants to acclimatize.

UDP-GalNAc (UDP-N-acetyl-D-galactosamine) disodium, a sugar nucleotide, serves as a substrate for EpsC115, an exopolymeric substances (EPS) N-terminal deletion mutant lacking residues 1-115. Additionally, UDP-GalNAc acts as the donor substrate for numerous N-acetylgalactosaminyltransferases, which transfer GalNAc from the nucleotide sugar to various saccharide or peptide acceptors [1].

Ziprasidone amino acid (Ziprasidone Impurity C), an impurity found in Ziprasidone, functions as a combined 5-HT (serotonin) and dopamine receptor antagonist, demonstrating significant antipsychotic activity [1].

Palmitoyl CoA lithium (Palmitoyl coenzyme A lithium) is a major component of fatty acids involved in the carnitine shuttle system, beta-oxidation, and the tricarboxylic acid cycle, and can be used to study metabolic disorders in the body.

PROTAC EZH2 Degrader-1 (Compound 150d) is a potent inhibitor that effectively suppresses EZH2 methyltransferase activity, with an IC50 of 2.7 nM. EZH2 plays a critical role in various tumorigenesis and development processes [1].

Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (Formula V) is a conjugate that combines a potent topoisomerase I inhibitor with an antibody agent conjugate (ADC) [1] via a specialized linker.