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Chemicals & Small Molecules

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    Results for Chemicals & Small Molecules ( 98424 )

      • 1-Epideacetylbowdensine

        Ref: T126530
        Sizes: 1 mg

        1-Epideacetylbowdensine is a useful organic compound for research related to life sciences and the catalog number is T126530.

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      • α-Conotoxin Vc1.1 TFA

        Ref: T73894
        Sizes: 1 mg, 5 mg, 25 mg, 10 mg

        α-Conotoxin Vc1.1 TFA is a peptide isolated from Conus victoriae and a selective nAChR antagonist that inhibits α3α5β2, α3β2 and α3β4, reversing mechanical allodynia in neuropathic pain models and can be used to study neuropathic chronic pain. α-Conotoxin Vc1.1 TFA inhibits human dorsal root ganglion nerve excitability and mouse colon nociception via GABA(B) receptors.

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      • Larsucosterol trimethylamine

        Ref: T74147
        Sizes: 1 mg

        Larsucosterol trimethylamine (DUR-928 trimethylamine) is a potent liver X receptor (LXR) antagonist that modulates endogenous epigenetics, reduces lipid accumulation in hepatocytes, attenuates lipopolysaccharide (LPS) and TNFα-induced inflammatory responses in macrophages, and alleviates LPS- and acetaminophen (ATMP)-induced multi-organ damage.

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      • 3’-O-(2-Methoxyethyl) inosine

        Ref: T75064
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 10 mg

        3'-O-(2-Methoxyethyl)inosine is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include inhibition of DNA synthesis and the induction of apoptosis, among others [1].

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      • Satralizumab

        Ref: T76712
        Sizes: 1 mg, 5 mg

        Satralizumab, a humanized monoclonal antibody and potent Interleukin-6 (IL-6) inhibitor, prevents the formation and progression of descending thoracic aorta aneurysm (dTAA) in Rattus norvegicus. It is also used in research for neuromyelitis optica spectrum disorder (NMOSD) and dTAA [1] [2].

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      • L-α-lysophosphatidylinositol sodium

        Ref: T77212
        Sizes: 1 mg

        L-α-lysophosphatidylinositol sodium is an endogenous ligand of GPR55 and an endogenous cannabinoid neurotransmitter that is involved in controlling cell survival and tumor progression.

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      • FDW028

        Ref: T77809
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 1 mL

        FDW028 is a selective and potent fucosyltransferase 8 (FUT8) inhibitor with anti-tumor activity that drives B7-H3 lysosomal degradation via defucosylation and CMA pathways. FUT8 can be used to study metastatic colorectal cancer (mCRC).

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      • FAK-IN-14

        Ref: T77811
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg

        FAK-IN-14 is a highly effective focal adhesion kinase (FAK) inhibitor that induces apoptosis and cell cycle arrest. FAK-IN-14 has weak inhibitory effects on Akt, c-kit, MEK1/2 and mTOR, but has significant inhibitory effects on FAK, FGFR1 and Pyk2.

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      • FAK-IN-15

        Ref: T77812
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg

        FAK-IN-15 is a highly potent focal adhesion kinase (FAK) inhibitor with antitumor activity.

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