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Chemicals & Small Molecules

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    Results for Chemicals & Small Molecules ( 96685 )

      • C2 Dihydro Ceramide (d18:0/2:0)

        Ref: T84383
        Sizes: 1 mg

        C2 Dihydro Ceramide (d18:0/2:0) (C2 Dihydroceramide) is a short-chain ceramide that is a precursor of ceramide synthesis and stimulates ABCA1-mediated cholesterol efflux.

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      • (−)-Apomorphine (hydrochloride hydrate)

        Ref: T84445
        Sizes: 50 mg, 10 mg

        (−)-Apomorphine, a non-selective dopamine receptor agonist, demonstrates pKi values of 6.43 (D1), 7.08 (D2L), 7.59 (D3), 8.36 (D4), and 7.83 (D5) for human recombinant receptors. It induces biphasic effects on locomotor activity and possesses anti-Parkinsonian and neuroprotective properties.[1,2,3,4]

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      • 6β-hydroxy Testosterone

        Ref: T84531
        Sizes: 1 mg, 5 mg, 10 mg

        6β-Hydroxy Testosterone, primarily metabolized from testosterone by CYP3A4 and CYP3A5 enzymes, represents 75-80% of testosterone's metabolites. Both cytochrome P450 enzymes, induced by glucocorticoids and various xenobiotics (including drugs and chemical carcinogens), facilitate the metabolism of xenobiotics and certain endobiotics like steroid hormones. However, the biological effects of 6β-hydroxy testosterone remain poorly understood.

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      • CAY10464

        Ref: T84540
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg

        CAY10464 (AHR antagonist 7) is a potent AHR antagonist with potential antitumor activity that inhibits CYP1A1 mRNA expression and may be used to study cancer and metabolic diseases.

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      • RCB-02-4-8

        Ref: T84666
        Sizes: 1 mg, 5 mg, 25 mg, 10 mg

        RCB-02-4-8, an ionizable cationic lipid designed for the formulation of lipid nanoparticles (LNPs), enhances mRNA delivery with proven effectiveness in increasing lung transfection efficiency in mice [1].

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      • BIBO3304 diTFA

        Ref: T84889
        Sizes: 1 mg

        BIBO3304 (diTFA), a selective neuropeptide Y (NPY) Y1 receptor antagonist, demonstrates oral efficacy. It exhibits high affinity for Y1 receptors in both humans and rats, with IC50 values of 0.38 nM and 0.72 nM, respectively. Additionally, BIBO3304 (diTFA) enhances bone-tendon healing via the Wnt/β-catenin signaling pathway [1] [2] [3].

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      • VH 101, acid

        Ref: T84920
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg

        VH 101, acid, a functionalized von-Hippel-Lindau (VHL) protein ligand, facilitates PROTAC research and development. It comprises an E3 ligase ligand and an alkyl linker featuring a terminal amine for easy conjugation to target protein ligands [1].

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      • Perfluorodecanesulfonic Acid

        Ref: T84953
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg

        Perfluorodecanesulfonic acid, a perfluoroalkyl substance (PFAS), has been detected in lake trout (S. namaycush).

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      • 1-Palmitoyl-2-Arachidonoyl-sn-glycero-3-PC

        Ref: T85255
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg

        1-Palmitoyl-2-Arachidonoyl-sn-glycero-3-PC (1-Palmitoyl-2-Arachidonoyl-sn-glycero-3-Phosphocholine) is a phospholipid found in biological membranes that contains palmitic acid (16:0) and arachidonic acid (20:0) in its structure. (16:0) and arachidonic acid (20:4) in its structure.

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