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    Results for Chemicals ( 21791 )

      • Homo-PROTAC cereblon degrader 1

        Ref: T13721
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg

        Homo-PROTAC cereblon degrader 1 (Legacy Tebubio ref. 282T13721). Homo-PROTAC cereblon degrader 1 is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3.

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      • Homo-PROTAC pVHL30 degrader 1

        Ref: T13722
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg, 1 mL * 10 mM (in DMSO)

        Homo-PROTAC pVHL30 degrader 1 (Legacy Tebubio ref. 282T13722). Homo-PROTAC pVHL30 degrader 1 is a potent PROTAC-based degrader of pVHL30.

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      • PROTAC FAK degrader 1

        Ref: T13840
        Sizes: 1 mg, 5 mg, 10 mg

        PROTAC FAK degrader 1 (Legacy Tebubio ref. 282T13840). PROTAC FAK degrader 1 is a selective and potent degrader of focal adhesion kinase (Fak) with an IC50 of 6.5 nM.

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      • PROTAC K-Ras Degrader-1

        Ref: T13844
        Sizes: 1 mg, 5 mg, 10 mg

        PROTAC K-Ras Degrader-1 (Legacy Tebubio ref. 282T13844). PROTAC K-Ras Degrader-1 is potent degrader of K-Ras based PROTAC.

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      • PROTAC PARP1 degrader

        Ref: T13845
        Sizes: 1 mg

        PROTAC PARP1 degrader (Legacy Tebubio ref. 282T13845). PROTAC PARP1 degrader is a degrader of PARP1 based on the PROTAC technology. PROTAC PARP1 degrader at 10 μM at 24 h inhibits MDA-MB-231 cell line (IC50 of 6.12 μM).

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      • PROTAC SGK3 degrader-1

        Ref: T13847
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 1 mL * 10 mM (in DMSO)

        PROTAC SGK3 degrader-1 (Legacy Tebubio ref. 282T13847). PROTAC SGK3 degrader-1 (SGK3-PROTAC1) is a PROTAC coupler that targets SGK3 and binds ligand to VH032 VHL, inducing degradation of endogenous SGK3. It inhibits GDC0941-induced proliferation of cancer cells. [5017-88-83-4]

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      • SMARCA-BD ligand 1 for Protac

        Ref: T13848
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 200 mg

        SMARCA-BD ligand 1 for Protac (Legacy Tebubio ref. 282T13848). SMARCA-BD ligand 1 for Protac is a compound that binds to SMARCA2, the BAF ATPase subunit, utilizing Protac technology to degrade SMARCA2.

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      • PROTAC BET Degrader-1

        Ref: T13849
        Sizes: 5 mg, 25 mg, 10 mg, 1 mL * 10 mM (in DMSO)

        PROTAC BET Degrader-1 (Legacy Tebubio ref. 282T13849). PROTAC BET Degrader-1 is a potent BET degrader utilizing the PROTAC mechanism.

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      • PROTAC BET degrader-3

        Ref: T13850
        Sizes: 5 mg, 25 mg, 10 mg

        PROTAC BET degrader-3 (Legacy Tebubio ref. 282T13850). PROTAC BET Degrader-3 is a potent degrader of BET proteins based on the PROTAC (PROteolysis TArgeting Chimera) technology.

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