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Click Chemistry

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    Results for Click Chemistry ( 905 )

      • N-(4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexane)-Doxo

        Ref: BP-24433
        Sizes: 100 MG, 50 MG, 250 MG

        N-(4-((2,5-dioxo-2H-pyrrol-1(5H)-yl)methyl)cyclohexane)-Doxorubicin is a maleimide attached Doxorubicin. It can conjugate with thiol containing molecules. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • MC-Val-Cit-Doxorubicin

        Ref: BP-24434
        Sizes: 25 MG, 50 MG, 10 MG

        MC-Val-Cit-Doxorubicin is a precursor of antibody drug conjugate. The maleimide can conjugate with thiol containing molecules. Doxorubicin is an anthracycline antibiotic with antineoplastic activity Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • 5-Hexynoic Acid-NHS Ester

        Ref: BP-24461
        Sizes: 100 MG, 500 MG, 250 MG

        5-Hexynoic Acid-NHS Ester contains a propargyl group and an NHS ester group. This reagent is an amine reactive reagent for derivatizing peptides, antibodies, amine coated surfaces etc. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • Bis-Sulfone-PEG8-acid

        Ref: BP-24476
        Sizes: 100 MG, 50 MG, 250 MG

        Bis-Sulfone-PEG8-acid is a PEG linker with a sulfone and acid end group. The sulfone group can be conjugated with thiol groups of proteins. The terminal carboxylic acid can react with primary amines in the presence of activators such as EDC and HATU to from stable amide bonds. The hydrophilic PEG chain increases the water solubility of the compound in aqueous media. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • Boc-Gly-Gly-Phe-Gly-OH

        Ref: BP-24479
        Sizes: 1 G, 500 MG

        Boc-Gly-Gly-Phe-Gly-OH is a self-assembly of N- and C-protected tetrapeptide, is a protease cleavable linker used for the antibody-drug conjugate (ADC). Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • SN-38

        Ref: BP-24513
        Sizes: 1 G, 10 G, 5 G

        SN-38 is an anti-tumor drug that is often linked to ADCs to be directly delivered to cells. It is also the active metabolite of the drug, irinotecan. Its mechanism of action is inhibition of DNA topoisomerase I, halting DNA synthesis and causing single-strand breaks in DNA.

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      • Boc-Val-Gly-OH

        Ref: BP-25144
        Sizes: 1 G, 500 MG

        Boc-Val-Gly-OH Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • 1,5-diazidopentane

        Ref: BP-25148
        Sizes: 100 MG, 250 MG

        1,5-diazidopentane is a linker with two azide groups which can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • 5-azidopentan-1-ol

        Ref: BP-25149
        Sizes: 100 MG, 500 MG, 250 MG

        5-azidopentan-1-ol is a linker containing an azide group and a terminal hydroxyl group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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