Results for Click Chemistry ( 905 )
Exatecan Mesylate is the salt of a hexacyclic chemical compound analogous to camptothecin and used as a payload in ADC research. Exatecan mesylate is used as an inhibitor of DNA topoisomerase I, which plays a key role in DNA replication, transcription, and recombination. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
Succinic acid is a dicarboxylic acid with a pair of carboxylic acid functional groups. The terminal carboxylic acid groups can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
Pimelic acid is a dicarboxylic acid with two carboxylic acid functional groups. The terminal carboxylic acid groups can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
Glutaric acid is a dicarboxylic acid with carboxylic acid functional groups at either either end of the molecular chain. The terminal carboxylic acid groups can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
methyl 3,4-dibromo-2,5-dioxo-2H-pyrrole-1(5H)-carboxylate is a small pyrrolidone molecule which features two bromine atoms and a methyl ester. The unsaturated dibromo motif is a covalent ligand for thiol groups, and may be used to label cysteine residues in proteins. The presence of two leaving groups on this molecule allows this linker to bind two thiols at a time. The methyl ester can be saponified to link this molecule to amines to form larger structures.
3,4-Dibromo-1H-pyrrole-2,5-dione is a small pyrrolidone molecule which features two bromine atoms and a free nitrogen. The unsaturated dibromo motif is a covalent ligand for thiol groups, and may be used to label cysteine residues in proteins. The presence of two leaving groups on this molecule allows this linker to bind two thiols at a time. The central amine can be alkylated or linked with carboxylic acids to form larger compounds.