Results for Click Chemistry ( 905 )
Biotin-PEG12-Gly-Gly-Gly is a cleavable PEG linker with a biotin group that can be used in the synthesis of antibody-drug conjugates. Biotin has strong binding affinity with avidin and can be used in detection, immobilization, targeting, labeling as well as nonradioactive purification. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
3-Azido-alcohol is a synthetic building block for adding an azide group with a hydroxyl handle. The azide group can react with alkyne such as BCN, DBCO, Propargyl group via Click Chemistry to yield a stable triazole linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
Fmoc-PEG3-Val-Cit is a PEG linker containing an Fmoc-protected amine and enzymatically cleavable Val-Cit group. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The Val-Cit is effectively cleaved by lysosomal proteolytic enzymes while being highly stable in human plasma, making this a potentent stragy in ADC linker design. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.