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Click Chemistry

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    Results for Click Chemistry ( 905 )

      • Fmoc-Val-Ala-PAB

        Ref: BP-27991
        Sizes: 1 G, 500 MG, 250 MG

        Fmoc-Val-Ala-PAB is a cleavable ADC linker. The Val-Ala is effectively cleaved by lysosomal proteolytic enzymes while being highly stable in human plasma, making this a potentent stragy in ADC linker design. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • Fmoc-Val-Ala-PAB-PNP

        Ref: BP-27992
        Sizes: 1 G, 100 MG, 500 MG, 250 MG

        Fmoc-Val-Ala-PAB-PNP can be used to design cleavable ADC linkers. The Val-Ala, as shown in the ACD Zynlonta, is effectively cleaved by lysosomal proteolytic enzymes while being highly stable in human plasma. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • 20-(tert-Butoxy)-20-oxoicosanoic acid

        Ref: BP-27993
        Sizes: 1 G, 5 G

        20-(tert-Butoxy)-20-oxoicosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) and in the synthesis of PROTACs. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • Exatecan

        Ref: BP-27996
        Sizes: 50 MG, 10 MG

        Exatecan is a hexacyclic chemical compound analogous to camptothecin and used as a payload in ADC research. Exatecan mesylate is used as an inhibitor of DNA topoisomerase I, which plays a key role in DNA replication, transcription, and recombination. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • Ansamitocin P 3

        Ref: BP-27998
        Sizes: 25 MG, 100 MG, 50 MG

        Ansamitocin P 3 is a macrocyclic antitumor antibiotic that works by depolymerizing microtubules in both interphase and mitosis, and perturbs chromosome segregation. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • Auristatin F

        Ref: BP-27999
        Sizes: 1 G, 100 MG, 500 MG, 250 MG

        Auristatin F is a cytotoxin that works as a microtubule inhibitor and vascular damaging agent. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • Dov-Val-Dil-OH, TFA salt

        Ref: BP-28002
        Sizes: 5 MG, 50 MG, 10 MG

        Dov-Val-Dil-OH, TFA salt is an intermediate of dolastoxin, a cytotoxic liner peptide that exhibits potent antitumor activity. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • N-Me-L-Ala-maytansinol

        Ref: BP-28006
        Sizes: 1 MG, 5 MG, 25 MG, 10 MG

        N-Me-L-Ala-maytansinol is a maytansine derivative and works as a microtubule inhibitor. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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      • DM1-SMCC

        Ref: BP-28008
        Sizes: 1 MG, 5 MG, 25 MG, 10 MG

        DM1-SMCC is a drug-linker conjugate composed of a potent microtubule-disrupting agent DM1 and a linker SMCC. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

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