Results for Click Chemistry ( 905 )
t-butyl-C18-D-Glu-OtBu is comprised of an octadecanedioic acid with a terminal t-butyl ester and a glutamic acid, which is also protected by a terminal t-butyl ester. The t-butyl protected carboxyl groups can be deprotected under acidic conditions. Glutamic acid is an α-amino acid that is used in the biosynthesis of proteins. This compound is also an intermedite in the synthesis of semaglutide. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
t-butyl-C18-D-Glu-OtBu-PEG2-acid is a PEG linker comprised of an octadecanedioic acid and a glutamic acid, which is also protected by a terminal t-butyl ester, with a terminal t-butyl ester and a carboxylic acid. The t-butyl protected carboxyl groups can be deprotected under acidic conditions. Glutamic acid is an α-amino acid that is used in the biosynthesis of proteins. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. This compound is also an intermedite in the synthesis of semaglutide. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
t-butyl-C18-D-Glu-OtBu-PEG2-amide-PEG2-azide is a PEG linker comprised of an octadecanedioic acid and a glutamic acid, which is also protected by a terminal t-butyl ester, with a terminal t-butyl ester and an azide. The t-butyl protected carboxyl groups can be deprotected under acidic conditions. Glutamic acid is an α-amino acid that is used in the biosynthesis of proteins. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. This compound is also an intermedite in the synthesis of semaglutide. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
t-butyl-C18-D-Glu-OtBu-PEG2-amide-PEG2-amine is a PEG linker comprised of an octadecanedioic acid and a glutamic acid, which is also protected by a terminal t-butyl ester, with a terminal t-butyl ester and an amine. The t-butyl protected carboxyl groups can be deprotected under acidic conditions. Glutamic acid is an α-amino acid that is used in the biosynthesis of proteins. The amine group is reactive with activated NHS esters, carbonyls (ketone, aldehyde) etc. This compound is also an intermedite in the synthesis of semaglutide. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
t-butyl ester-PEG4-Val-Cit-PAB-MMAE can be used antibody drug conjugation as a precursor. It contains a PEG4 spacer, a protease-sensitive Val-Cit dipeptide, a PAB linker and an MMAE payload. It can be attached to a monoclonal antibody (MAB) which directs it toward cancer cells. Under acidic conditions, the t-butyl group can be removed. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
Boc-5-aminopentanoic NHS ester is a linker containing an NHS ester and a t-Boc protected amine group. The t-Boc group can be deprotected under mild acidic conditions to form a free amine. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.