Lipids & Polymers

Iberdomide is a derivative of Thalidomide and has antitumor and immunostimulatory activities because it is a potent cereblon (CRBN) E3 ligase modulator. Reagent grade, for research use only.

CC-90009 is a modulator of the E3 ligase cereblon (CRBN), binding to cereblon and leading to the induction of ubiquitination and proteasomal degradation of GSPT1. Reagent grade, for research use only.

CFT7455 is an orally active compound that degrades zinc finger transcription factors Ikaros (IKZF1) and Aiolos (IKZF3). It is an anti-cancer agent that binds with high affinity to the cereblon E3 ligase, making it useful in PROTAC development. Reagent grade, for research use only.

NVP-DKY709 is a highly potent inhibitor of IKZF2, designed for cancer research and PROTAC development. Reagent grade, for research use only.

DBCO STP ester is a water-soluble reagent with a terminal DBCO group and a STP ester group. DBCO STP ester that can be used for the modification of peptides, antibodies, proteins, and other molecules containing the amine group. The STP esters are excellent alternatives to conventional N-hydroxysuccinimide (NHS) esters for coupling reactions in aqueous environments. The DBCO groups is commonly used for copper-free Click Chemistry reactions due to its strain promoted high energy. Reagent grade, for research use only.

Alkyne-PEG2-iodide is a crosslinker containing a propargyl group and an iodine group. The propargyl group can form triazole linkage with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry reactions. Iodine (I) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media. Reagent grade, for research use only.

Palmitoleic acid is an unsaturated fatty acid that contains 16 carbon atoms and a double bond seven carbon atoms from the end of the chain. Reagent grade, for research use only.

FMOC-L-LYS[OCT-(OTBU)-GLU-(OTBU)-AEEA-AEEA]-OH is a useful research chemical used in the preparation of semaglutide. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

DBCO-C5-PEG12-acid is an analog of DBCO-Acid with PEG linker and a DBCO group. DBCO group is a highly reactive cycloalkyne which is commonly used for copper-free Click Chemistry reactions. The hydrophilic PEG chain allows for increased water solubility of compounds in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. HATU) to form a stable amide bond. Reagent grade, for research use only.